Featured Articles from Philly.com

The blood-pressure-lowering drugs known as ACE inhibitors are a mainstay of treatment for many diseases. But with growing use of these heart-helping medications, more and more patients are winding up in emergency rooms with a rare side effect that most have not been warned about: swelling around the face and neck. In the worst cases, the patient's tongue and throat become hugely bloated, closing the airway. No medications can slow or reverse this swelling, called angioedema.

‘Brainy's the new sexy. " So declares one of Sherlock Holmes' most formidable, if scandalously flirtatious, adversaries, Irene Adler in A Scandal in Belgravia, a new installment in the BBC's superb drama Sherlock, which returns for a second season Sunday on PBS' Masterpiece Mystery. Scandal will be followed by two other feature-length Holmes mysteries. Irene, played with keenly sentient sensuality by Lara Pulver (True Blood, MI-5), is referring to Arthur Conan Doyle's famed brainiac, but she might as well be talking about the series.

LOS ANGELES - Millions of people have endured a colonoscopy, believing the dreaded exam may help keep them from dying of colon cancer. For the first time, a major study offers clear evidence that it does. Removing precancerous growths spotted during the test can cut the risk of dying from colon cancer in half, the study suggests. Doctors have long assumed a benefit, but research hasn't shown before that removing polyps would improve survival - the key measure of any cancer screening's worth.

LOUISVILLE, Ky. — It was shortly after 7 a.m. Sunday, barely 12 hours after a Kentucky Derby that had been 6 months in the planning went very wrong in less than a second. Michael Matz was walking a horse named Welcome Dance around the Barn 42 shedrow, passing a sedate Union Rags, peering out from his stall. As he rounded the corner, Matz called back over his shoulder: "We did everything we wanted except the last 2 minutes and that was the part we couldn't help. " In horse racing, you can be prepared, organized and make rational decisions.

Weeks before prosecutors say he tried to rape a 14-year-old boy, the Rev. James J. Brennan called the clergy office at the Archdiocese of Philadelphia. At the time, Brennan had just started a leave of absence to deal with "inner turmoil" he blamed in part on being sexually abused as a child. Brennan complained to Msgr. William J. Lynn, who ran the clergy office, that other priests had been gossiping that he really took the leave so he could "shack up" with one of his former students at Cardinal O'Hara High School.

A new J.C. Penney and Nordstrom Rack are centerpieces of a planned expansion announced Thursday at the site of an old Strawbridge's department store at the Willow Grove Park mall. The stores, set to open in 2012, will be part of 190,000 square feet of renovated space reconfigured from the three-story shell of the Strawbridge's, according to the Pennsylvania Real Estate Investment Trust, which owns the mall. The stores are being slotted into a long-dormant site that was originally to have come back to life as a Boscov's.

WHAT'S IN a name? Plenty, if you're a casino looking to expand your business. On Friday, what has been Harrah's Chester Casino and Racetrack since its 2006 opening will officially be rebranded Harrah's Philadelphia. (Its website already was calling it that on Tuesday.) "The [new name] is to complement the changes and evolution we're bringing to the property," said Ron Baumann, the gambling den's senior vice president and general manager, in reference to in-the-works upgrades of amenities including dining and entertainment.

Fannie Mae and Freddie Mac are adopting new guidelines to streamline the process for short sales, which most real estate observers expect will outpace foreclosures in the coming year. The guidelines, required by the Federal Housing Finance Agency and effective June 15, would require servicers of mortgages backed by Freddie and Fannie to review and respond to requests for short sales within 30 calendar days of receipt of a buyer's offer. A short sale is a transaction in which a lender agrees to accept less than the amount owed on the mortgage.

INSIDE JAROMIR Jagr's locker stall, in the bowels of the Wells Fargo Center and any arena where the Flyers play, a small memento is wrapped in blue felt. It is a trifold, no more than 6 inches in length. It sits next to Jagr's hockey tape, stick wax, and various weights and braces and training contraptions. It does not stand out, except for the shine reflecting off the gilded hand-painted faces of the Eastern Orthodox Church's Holy Trinity, and the fact that religious icons in hockey dressing rooms are rarer than Stanley Cup-clinching goals.

Does Lamar Odom blame his wife for ruining a potentially great NBA career? Does Lamar, effectively booted by the Dallas Mavericks, think Khloé Kardashian loves her career as one of the principals in The Kardashian Un-Reality Industry more than her marriage? Does he want to leave her? These questions haunt us at night. Khloé, too, by the sounds of it. The embattled reality star, who this week announced she and Lamar are temporarily benching their reality show, Khloé & Lamar, tells People mag there are bumps in her marriage.

Terrell Owens faces off with three of his four baby-mamas on Tuesday's episode of "Dr. Phil" (4 p.m., CBS3). Women named Kimber, Monique and Melanie claim the former Eagles wide receiver is delinquent on child-support payments and has little to no relationship with their kids that he fathered. Owens tells Dr. Phil he squandered most of the $80 million he had been paid in the NFL and blamed his travel schedule and living in different cities from the kids as to why he can't see them.

MAYS LANDING, N.J. — Dan Danchak was supposed to meet April Kauffman at his American Legion post in Somers Point on Friday night to smoke a "victory cigar" with her. Instead, Danchak, a Vietnam veteran who had worked with Kauffman, and her husband, James, a prominent area physician, on veterans' health care issues, was mourning her death. The 47-year-old Kauffman, a grandmother, local radio personality, and entrepreneur known affectionately by friends as "Air Strike April," was found shot to death in the master bedroom of her Linwood home on Thursday morning.