Charles Barkley's 29 points and 18 rebounds and a brilliant performance by Cliff Robinson (27 points, 11 boards) were rendered meaningless by the suddenly determined Warriors.
The Warriors, who were led by Rod Higgins with 28 points and Eric ''Sleepy" Floyd with 24, improved their record to 2-10.
Golden State's only previous victory had come over the Los Angeles Clippers. So the Sixers (4-5) became a member of a select group.
The Sixers led, 94-84, with just over five minutes left in the game after Barkley hit a three-pointer.
But the Warriors brought the 14,617 fans alive with a 14-2 run that gave them the lead for good.
"Just because they were 1-10, you can't count them out," said Maurice Cheeks. "They are still professionals. They did what they had to do to win, and we didn't."
Roy Hinson said the Sixers didn't take the Warriors lightly despite their record.
"We went out with the idea that we were not going to let that (their record) affect us. We were going to play hard and let things fall where they may."
In the first half, the Sixers and the Warriors played equally ragged from the tipoff and fittingly, the game was tied, 50-50, at intermission.
The Sixers played the last 4 minutes, 57 seconds with the 6-foot-8 Danny Vranes at center and the Warriors 7-footer Joe Barry Carroll, often noted for his ability to sleep and play basketball at the same time, went without a field goal during that span.
Vranes was in the game largely because of the 11 fouls that were called on the Sixers in the second quarter.
Tim McCormick, Roy Hinson and David Wingate had three fouls each and the Warriors spent most of the second period sharpening their free-throw shooting.
The Sixers, thanks to the ineptitude of the Warriors and the play of Robinson, managed to stay in the game.
Philadelphia was down by 10 points with 5:15 left in the second period when Robinson and Barkley went on a much-needed mission.
The two Sixers scored six points each over a span of 2 minutes and 21 seconds to cut Golden State's lead to 49-44.
Then it was the Sixers' turn at the foul line and they connected on four in the last 1:40 and got a rebound basket from Vranes to overshadow the one free
throw the Warriors got in the last 2:53.
If the Sixers were bad in the second quarter, their play in the opening period defied description.
Barkley, who has had slow starts in the last two games, was curiously out of sync again in the early stages.
The Sixers, who were missing layups, free throws and everything aimed at the basket, hit only six of 28 shots and fell behind, 23-17.
At the same time, Philadelphia was being victimized by the likes of rookie Tellis Frank, Higgins and just about anybody in a purple and gold uniform except Carroll.
The second quarter wasn't two minutes old when the Sixers first trailed by 10 points, 31-21.
They closed the gap to six points before they were besieged by a dirth of whistles from the referees.
Once the Warriors started going to the free throw line, however, they seemed to forget how to make a field goal.
That's when Robinson, a saviour with 14 points and six points in the first half, got cranked up and Barkley kept his better-late-than-never streak intact.