Willingboro showed some signs of life after intermission. But by then, the Lancers (7-1) had already built a 31-12 lead.
"We felt kind of slighted that they had picked us for homecoming," Holy Cross quarterback Rob Curley said. "So we wanted to come out and put something on them."
In the end, the Lancers compiled 454 yards of total offense and 18 first downs. Holy Cross scored on its first five possessions and punted once.
Curley, wideout Rob DeVeney, and tailback Eric Foxworth did most of the damage.
Curley completed 13 of 19 passes for 330 yards and three touchdowns to go with an interception. Two of the senior's touchdowns and 223 of his passing yards came in the first half.
Curley has thrown for 675 yards and eight scores in back-to-back weeks against Timber Creek and Willingboro.
DeVeney was the quarterback's top target yesterday. The junior had four receptions for 179 yards and two scores, covering 52 and 60 yards.
Meanwhile, Foxworth rushed for a team-high 99 yards and two touchdowns on 20 carries.
"We got out of the box really well," Holy Cross coach Jerry McConnell said. "Our offense, the last two weeks, seems to be getting significantly better. It seems like we are starting to click.
"And Curley, the last two games, has been phenomenal."
Willingboro was able to close the gap to 16 points mostly because of Mateen.
After missing last week's game with a slight concussion, the senior had 161 yards and a touchdown on 22 carries.
However, impressive statistics were the farthest thing from Mateen's mind after the game. His thoughts were on losing a homecoming game to Holy Cross.
"I don't like Holy Cross," he said. "I wanted to beat them. That's all I wanted."
Contact suburban staff writer Keith Pompey at 856-779-3826 at kpompey@phillynews.com.