Although the Quakers outrebounded Miami in the first half, 21-15, the Red and Blue were done in by 14 turnovers and trailed at the half, 38-28.
Miami (13-1) led the entire game, though the Quakers did cut the lead to five twice in the first half.
Cameron Lewis was a bright spot for the Quakers, rattling off six straight points in the first half to pick up his team. With a total of 13 points, Lewis was the only Penn player in double figures despite foul trouble that limited his time in the second half.
"We just made a lot of mistakes," Lewis said.
After the halftime break, Miami quickly doubled the size of its 10-point lead. The Hurricanes opened the half with an 11-0 run, led by back-to-back baskets by Dwayne Collins. Collins had a stellar night, finishing with 18 points. Teammate Brian Asbury led all scorers with 22.
"We knocked a lot of balls loose, caused 21 turnovers and scored a lot in transition," Miami coach Frank Haith said. "I thought that's what got us going in the second half."
The Hurricanes led by 33 at one point during the second half.
"I think our defense, up until the second half today, has improved," Penn coach Glen Miller said. "It's just that you need to be able to put 40 minutes together, whether you're playing Miami or our next opponent."
Miller tinkered with the lineup, starting Andreas Schreiber and Lewis, who had previously combined for just six starts the entire season.
"The rationale is that we scored six points in a half," Miller said, referring to Saturday's debacle. "We got beat by 30 points to a decent team, but not a Top 25 team, and it was just time to change the lineup and mix it up a little bit."
Grandieri, usually effective for the Quakers, struggled last night, finishing with seven points on 3-for-5 shooting.
Tyler Bernardini added nine points for Penn. Kevin Egee led the team with seven rebounds.
The Quakers return to action Saturday with a home game against New Jersey Institute of Technology. *