PICK: CHARGERS
Key matchups
1. Eagles WRs DeSean Jackson and Jeremy Maclin vs. Chargers CBs Antonio Cromartie and Quentin Jammer: Jackson and Maclin need to be factors for the Eagles to win. Cromartie and Jammer can be exploited if Donovan McNabb has time to throw deep. Advantage: Eagles
2. Eagles OTs Jason Peters and Winston Justice vs. Chargers OLBs Shawne Merriman and Shaun Phillips: Merriman and Phillips have combined for seven sacks in the last two games. Peters is playing on a bad ankle and Justice is unreliable. Advantage: Chargers
3. Eagles CBs Asante Samuel and Sheldon Brown vs. Chargers WRs Vincent Jackson and Malcolm Floyd: Samuel and Brown have combined for nine interceptions this season, but are going to have problems dealing with Jackson's and Floyd's size. Both are 6-5. Advantage: Chargers
Hot and not
HOT:
Eagles: DE Trent Cole. Has team-high 7 1/2 sacks, team-high 11 hurries and five tackles for losses.
Chargers: WR Vincent Jackson. Has 18 receptions for 303 yards and four TDs in the last three games. Had the game-winning TD catch Sunday vs. Giants.
NOT:
Eagles: QB Donovan McNabb. Has completed just 56.4 percent of his passes in the last four games and has been sacked 15 times in his last 124 attempts.
Chargers: RB LaDainian Tomlinson. Is averaging just 3.2 yards per carry. Had 22 yards on 12 carries last week vs. Giants.
Domowitch's prediction
Chargers 31, Eagles 24
