The Donor Sibling Registry reports more than 7,400 matches through the service since its founding in 2000. Nearly 28,000 donors and offspring are registered.
Cairo of CryoGam believes failure is more likely than success in attempts at donor-offspring bonding - another reason she supports donor anonymity. Those who wish to remain anonymous should be able to do so, she said.
"Sometimes these donors are 19 or 20. They don't think that far down the road," she said. "Some might even forget they were a donor in college, and then suddenly there's a person on their doorstep. They're not family. They're genetically linked."