A 20-year-old woman was pronounced dead at Temple University Medical Center, and a 21-year-old man was injured.
No charges had been filed, Vanore said.
Eric Jones, a resident who was awakened by the crowd and went outside to investigate, said a woman had been escorted out of the bar and had gotten into a Chevrolet sedan.
A man smashed its windshield with a brick, Jones said.
He said he had heard three gunshots.
"I saw there was a fight, and I told them to get away from my property," said Jones, who lives in one of the few houses on the block.
The woman drove away alone, circled the block, and returned to the club, speeding, Jones said.
He said that she appeared to avoid a crowd that had gathered in the street, but threw her hands over her face as her car smashed into several pedestrians on the sidewalk.
Angry bystanders surrounded her car and kicked in its windows, Jones said. "Every weekend in that club, there's a fight," he said. The club closes at 6 a.m.
Police towed away several damaged vehicles Saturday, leaving behind broken glass and shreds of yellow crime-scene tape.
Club Motivation's awning proclaims the "best food and drink in town." Phillygaycalendar.com describes it as a "huge" venue with a 3,500-square-foot dance floor.
Telephone and e-mail messages left for Club Motivation's owner were unanswered.
Contact staff writer Andrew Maykuth at 215-854-2947 or amaykuth@phillynews.com.