The benefits of moderate alcohol consumption - reduced risk of heart disease, stroke, gallstones, diabetes, and death from a heart attack - are well-documented. There's even evidence that alcohol helps keep the mind sharp as one ages.
No one has ever associated pot consumption with mental acuity. Quite the opposite: Marijuana use has been shown to impair memory and inhibit learning ability. Among students, marijuana use is strongly associated with lower test scores and lower educational attainment. Chemically, marijuana is more like "harder" drugs - cocaine, heroin, speed, and the psychedelics - than a glass of wine or a cocktail. One study found that extended use may even lead to psychosis.
There are physical effects, too. Lung researchers report that smoking a couple of joints does more damage than a whole pack of Marlboros, and contains toxic compounds like ammonia and hydrogen cyanide. For many, pot is addictive. A study in the Journal of the American Medical Association found that more than 30 percent of pot smokers were dependent on the drug to the point of demonstrating signs of withdrawal and compulsive behavior. Reports from drug-abuse help lines and treatment facilities show that marijuana addiction is a major problem.
Negative social effects abound as well. Take crime. Amsterdam shows what happens when marijuana is available, legally and in abundance. Amsterdam is one of Europe's most violent cities, and Dutch officials pin the blame on their liberal drug policies. A report by four government ministries finds that drug-related crime places a heavy burden on local authorities and that criminal organizations are increasingly muscling their way into the drug market, using it as a base for international operations.
As California debates legalization, Dutch officials are retooling their laws and shutting down marijuana dispensaries "to tackle the nuisance associated with them and manage crime risks more effectively."