Many biologists beg to differ: Evolution isn't completely random, they say, and neither is it geared to produce humans.
The pope's words raise the question: Are Catholicism and evolution in conflict?
Several prominent Catholic scientists said their religion was perfectly compatible with science, and the only apparent problem in the homily came from the way the pope mischaracterized evolution as random. Far from being haphazard, natural selection imposes order on the natural world, as do the laws of physics and chemistry.
If the pope knew biology as well as he does theology, he'd be well within scientific consensus, said Brown University biologist Ken Miller, who is Catholic. "The pope needs a science adviser."
Others say statements in the homily reflect a long-standing schism between science and the Catholic faith.
Catholicism let go of the idea that the Earth is the center of the universe and accepts that evolution happened, but it still views mankind as having a special place in the cosmos, shaped partly by evolution and partly by the divine endowment of a soul. The Catholic scientists also see mankind - or some rational being - as part of the purpose of evolution.
Catholics "cannot accept evolution as we scientists accept it - as an unguided, materialistic process with no goal or direction," said University of Chicago biologist Jerry Coyne, who writes about science and religion in his blog, "Why Evolution Is True."
All agree there is order and majesty in nature. But they disagree over how it got here.
Many religious people see life as a symphony, all the notes carefully written by a divine composer. Nonreligious scientists see it more as an improvisational riff - or a comedy improv - with creativity emerging organically from within, free of any outside scriptwriter.