Hardin said steroids would have been so "incredibly inconsistent with his career and beliefs that there's no way he would have done it."
Clemens has said that the only things McNamee ever injected him with were the common local anesthetic lidocaine for his joints and vitamin B-12 to ward off flu viruses and stay healthy. But Durham said neither substance was found on the needles or cotton swabbed with his blood stains.
Hardin told the jury that the government is "horribly wrong" in charging his client with perjury, false statements, and obstruction of Congress. Clad in a dark suit, Clemens watched silently from the defense table with a clenched jaw.
"There was a rush to judgment on Roger that has made it impossible for him to be fairly heard until he got here," Hardin said in the federal courthouse just a couple of blocks from the congressional hearing room where Clemens testified three years ago.
Durham, however, said that about 45 witnesses, including several of Clemens' former teammates, will help make the case that Clemens used anabolic steroids and human growth hormone. When Clemens denied the use under oath before a House panel in 2008, Durham said, "it was false and he knew it was false."
Hardin argued that the government's case essentially rises and falls with McNamee, who the lawyer said has lied repeatedly. "He's still lying," Hardin said.
Hardin also said that McNamee lied in a police investigation in Florida in 2001. The trainer was investigated for sexual assault, but Walton had previously instructed Hardin not to discuss specifics of that probe in front of the jury.
Hardin tried to fight the perception that Clemens arrogantly insisted on testifying before Congress to protect his legacy and thus put himself in this criminal position. He was not subpoenaed to testify and Hardin says it was "technically true that he voluntarily appeared" though under tremendous pressure.
"Roger Clemens, unless he was comatose, always knew the danger of him testifying," Hardin said.
"Did he [Clemens] do it out of arrogance and wanting to go to the Hall of Fame?" Hardin said. "Really? To get into the Hall of Fame? Really? Is that what we've come to?"
Hardin objected during Durham's opening argument when the prosecutor told jurors that Clemens teammates Andy Pettitte, Chuck Knoblauch, and Mike Stanton would testify they used performance-enhancing drugs to recover from injuries and because the pressure to perform was so high in Major League Baseball.
Durham showed a photo of the yellowing cotton balls, needles, and vials turned over by McNamee, whom the prosecutor described as "a man that was hand-chosen by Mr. Clemens to train him." He said the evidence was tested by two California labs - one that found Clemens' DNA on the needle and cotton and another that tested them for drugs.
"They found absolutely no B-12, and they found absolutely no lidocaine," Durham said. "What they did find was anabolic steroids."
McNamee says he collected the evidence in 2001, when Clemens became the first pitcher ever to start a season 20-1, led the Yankees to the World Series, and won his sixth Cy Young.
Durham said McNamee saved the material - the photo showed the Miller Lite can that McNamee kept it in for more than six years - because he was always skeptical he could trust his star client if steroid allegations ever surfaced and that he would be "thrown under the bus." Durham said McNamee did not initially tell federal agents about it, but only did so after Clemens went on CBS's 60 Minutes and smeared his name.