Brophy put in Rancocas Valley's first and seventh penalty kicks, while Sanders (10 saves) stopped two shots in the shootout.
South Jersey Group 2. Middle Township needed a goal by Rodrigo Loureiro to tie the score at 2-2 with 3:30 to go in the second half, and the fourth-seeded Panthers completed the comeback when Loureiro converted Township's final shot to edge No. 5 seed West Deptford, 5-4 in penalty kicks.
Kyle Stanford, Kent Miller, Tyler Leonard and Jacob Cowan also scored in the shootout for the Panthers, while goalie Steve Hand stopped two penalty kicks.
Doug Denny scored twice and Nick Stone supplied shutout goaltending as seventh-seeded Delran upset No. 2 seed Woodstown, 2-0.
Vincent DelDuca faced just three shots in posting a shutout, and three players provided the scoring for top-seeded Haddonfield's 3-0 victory over No. 9 seed Cinnaminson.
Richard Wright headed in Matt Taylor's chip into the box with 15:07 left in regulation, and Jon Weaver (six saves) recorded his 12th shutout of the season as third-seeded Haddon Heights scuffled past No. 11 seed Pemberton, 1-0.
South Jersey Group 3. Top-seeded Timber Creek advanced to the semifinals by outscoring No. 8 seed Moorestown in penalty kicks, 3-2.
Alex Kourahanis, Jeffrey Morgan and Sonimi Halliday converted for the Chargers, and keeper Andrew Garcia made a diving stop to his left on Moorestown's final shot.
Cody Chladek and Kent Dimmig scored nine minutes apart early in the second half, sending fifth-seeded Seneca to a 2-0 triumph at No. 4 seed Burlington Township. Eric Bihlear set up both goals, giving him 16 assists for the season, and Ryan Oyola posted his seventh shutout.
Zack Sakena cashed in a pass from Max Berardis in the second half for the game's lone goal, making second-seeded Ocean City a 1-0 winner over No. 7 seed Oakcrest.