This was the last game for Upper Perkiomen coach Keith Leamer, who resigned earlier this week after eight seasons at the helm.
With the win, Boyertown (6-6 overall, 3-6 league), leads the rivalry, 9-3, and has won three of the last four meetings with the Indians (5-7, 3-6).
Pottstown 49, Owen J. Roberts 6 - Malik Brinkley rushed for five touchdowns and Pottstown (4-8, 3-6) easily turned away the visiting Wildcats (1-11, 0-9).
Corey Baker aided Brinkley with a game-high 176 rushing yards and two touchdowns.
Central League
Mike Clancy rushed for two touchdowns, and Haverford High held off visiting Upper Darby, 21-16, to secure its second straight rivalry win.
Upper Darby still leads the traditional holiday rivalry that began in 1910, 43-41-6.
Clancy's 2-yard run in the third quarter put Haverford (7-5, 5-4) ahead, 21-10, before Fred Thorpe tacked on an Upper Darby (3-9, 2-7) touchdown in the fourth.
Nonleague
Legende Whitfield returned a kickoff 52 yards for a touchdown as Imhotep Charter rallied to top visiting Boys' Latin, 13-6.
Whitfield's first-quarter return handed the Panthers (8-4) a 7-6 lead before Eerin Young rushed for a touchdown in the third period to beat Latin for the second straight year. Mike Hammock hauled in a 34-yard pass to put the Warriors (7-5) on the board in the first quarter.
West Philadelphia 26, Overbrook 0 - For the first time in 10 years, the Speedboys (11-1) knocked off visiting Overbrook (4-7). The win is West's 11th of the season, a school record. Desmond Sams led the way with two rushing touchdowns, including a 54-yard sprint to open the scoring.
Frankford 49, Fels 26 - Mike Brown racked up five touchdowns as the Pioneers (8-3) ran away with an easy win over visiting Fels (4-8) for the second straight year.
Brown caught three touchdowns, rushed for another, and returned a kickoff to the end zone. Quarterback Tim DiGiorgio threw four touchdowns for Frankford.