Fine has been accused of child sexual abuse by three men, including two former Syracuse ballboys. Fine, who was fired Sunday, has denied the allegations.
Boeheim said his apology and regrets came from the heart. "No one said this is what you should say," he said. "This is what I feel."
When the allegations first surfaced, Boeheim adamantly defended Fine and accused the men of lying for money.
"What I said last week was out of loyalty," he said. "I acted without thinking. I couldn't believe what I was hearing."
Advocates for sex abuse victims had called for Boeheim to resign or be fired for his disparaging remarks.
Boeheim said his initial comments were "insensitive to the individuals involved and especially to the overall issue of child abuse."
Boeheim said he spent time this week at the McMahon Ryan House for child abuse in Syracuse and plans to get involved to help raise awareness.
"They need to get the message out," he said. "I'm going to do everything I can to do that, whether I'm coaching or not coaching."
In Friday's game, Brandon Triche had 20 points and Neumann-Goretti's Scoop Jardine added 16 for the Orange (8-0).
Kenny Boynton led the Gators (5-2) with 22 points.
Just as he was on Tuesday's home win over Eastern Michigan, Boeheim was greeted by a nice ovation when he was introduced to a crowd of 24,459 that included former Syracuse star Carmelo Anthony and former Orange assistant Rob Murphy, in his first year at the helm at Eastern Michigan, in front-row seats.
Earlier Friday, USA Basketball said Boeheim's spot on the coaching staff of the U.S. basketball team remained secure, though the U.S. Olympic Committee is monitoring the investigation of Fine.
Boeheim is the top assistant to Mike Krzyzewski on the team that will play at the 2012 London Olympics.
The USOC declined comment. Because Boeheim does not fall under the USOC's umbrella until the Olympic team is officially named, the USOC does not consider his status on USA Basketball to currently be its issue.
Louisville 62, Vanderbilt 60 - Peyton Siva made a layup and Chane Behanan stole the ball with two seconds left to give the host No. 6 Cardinals (7-0) an overtime win over the No. 20 Commodores (5-3).
Pitt's Woodall out
Pittsburgh junior point guard Travon Woodall is out a month with a groin strain and an abdominal tear and will need four to five weeks of rest but will not require surgery.
Woodall is averaging 14.1 points, 8.3 assists and 3.4 rebounds for Pitt (6-1), which plays at Tennessee Saturday.
Notre Dame 69, Penn 38 - Devereaux Peters had 16 points as the No. 3 Irish trounced the Quakers (4-2) in South Bend, Ind. Kara Bonenberger led Penn with nine points and seven rebounds.
Rutgers 63, Florida 49 - Erica Wheeler scored 15 points, and April Sykes and Monique Oliver added 12 points as the No. 11 Scarlet Knights (8-0) thumped the Gators (6-2) in Daytona Beach, Fla.