Teaming with talent-search mogul Simon Cowell and Sony, Overbrook - named for Smith's Philly high school alma mater - will help create televised hunts for the world's best DJs, for broadcast in the United States and Britain.
Smith's actress wife, Jada Pinkett-Smith, will have an active leading role, along with Overbrook's Miguel Melendez, according to Wednesday's announcement.
"As soon as I met Jada and Miguel from Overbrook, I knew they would be our ideal partners," said Cowell, who worked with Sony to produce Fox's The X Factor and NBC's America's Got Talent. "DJ's are the new rock stars. It feels like the right time to make this show."
Broadcast networks and show names were yet to be announced.
Will and Jaden Smith, who starred together in The Pursuit of Happyness, have been shooting scenes for After Earth (previously titled 1000 AE) about a father and son who crash on a future, supposedly uninhabitable Earth.
The Sixers could not confirm if Jaden will also attend tonight's game.
Will Smith's comic sci-fi sequel, Men in Black III, should be one of this summer's heavyweights, having already elbowed its way into the primo Memorial Day weekend slot. It opens Friday, May 25.
It will be Smith's first major movie role since Seven Pounds was released in Decemeber 2008.
Contact staff writer Peter Mucha at 215-854-4342 or pmucha@phillynews.com.