Late in the first quarter, he was the subject of a successful Eagles reversal. On second and 10 from the Eagles 20, the officials ruled that Michael Vick's pass to Jackson was incomplete.
Eagles coach Andy Reid challenged the call, and it was reversed to an 11-yard gain. Jackson somehow got his arms under the ball before it hit the ground.
The Eagles wouldn't score on that drive, but would late in the first half when Vick hit a wide-open Jackson in the end zone for a 19-yard touchdown pass with 1 minute and 47 seconds left in the second quarter.
Jackson got well behind Giants safety Antrel Rolle for the score.
"It was a great play call, and all week in practice we've been running it," Jackson said. "On the film it showed if I got a good inside release on Corey Webster and get the attention of Antrel Rolle and turn my head and look back at Vick, they thought I was going to go to the post and from there I flipped out and went to the corner route, and Mike Vick threw a great ball."
In the first half, Jackson was targeted five times and he had three receptions for 62 yards. His other first-half catch was a 32-yard reception that got the Eagles out of some difficult field position on a third-and-11 play from their own 9-yard line.
In the third quarter he had a 14-yard reception during the Eagles first drive that eventually resulted in a 20-yard Alex Henery field goal.
Jackson made a key 19-yard reception in the fourth quarter of a drive that put the Eagles ahead, 19-17, when Henery kicked a 26-yard field goal with 1:49 left.
With 99 receiving yards on Sunday, Jackson just missed achieving the 15th 100-yard receiving game in his career.
He'll take the 'W,' one that was accomplished with the Eagles not committing a single turnover.
"Mike Vick did a great job of throwing the ball, and everybody did a better job protecting the ball, and it is what we worked on all week in practice," Jackson said.
His performance on Sunday night was redemptive after Jackson was held to just three receptions for 43 yards in last week's loss. He was also stopped 1 yard short of a touchdown on a 14-yard pass reception.
This time neither he nor the Eagles would be stopped.
Contact Marc Narducci at mnarducci@phillynews.com, or follow @sjnard on Twitter.