E. Donnall Thomas, a physician who pioneered the use of bone-marrow transplants in leukemia patients and later won the 1990 Nobel Prize in medicine, has died in Seattle at age 92.
The Fred Hutchinson Cancer Research Center announced the death Saturday. A spokesman said the cause was heart disease.
Thomas' work is among the greatest success stories in the treatment of cancer. Bone marrow transplantation and its sister therapy, blood stem cell transplantation, have improved the survival rates for some blood cancers to upward of 90 percent from almost zero.