The impact sent the Cavalier across the intersection, where it sideswiped a utility pole and crashed into a clothing collection bin before stopping, Browne said.
The Camry also continued across the intersection onto the property of a shed company. The car hit a large rock, vaulted into the air and hit several sheds before coming to rest about 300 feet from the initial point of impact, Browne said.
"It looks like a war zone down there," Browne said.
The drivers – both women – were pronounced dead at the scene, Browne said. Police had not released their names as of late Sunday afternoon. They said only that the driver of the Cavalier was born in 1980, and the driver of the Camry in 1963.
A male passenger in the Cavalier was transported to Lehigh Valley Hospital with what were not believed to be life-threatening injuries, Browne said.
An investigation into the cause of the accident is continuing, with speed considered a major factor, the officer said.
The I-95 accident occurred at 6:20 p.m. in Bensalem Township.
A car driven by 19-year-old Carlee Tran left the roadway's southbound lanes, hit a guardrail and "became airborne," state police said in a news release. Tran's car landed in a northbound lane and was hit by a second car, driven by Brian McHugh, 51. A third car also hit Tran's car before her vehicle came to rest upside down, police said.
Tran, of Philadelphia, and McHugh, of Pennington, N.J., were pronounced dead at the scene, police said. The driver of the third car was taken to St. Mary Medical Center in Langhorne with injuries of "unknown severity," police said.
Northbound lanes on I-95 were closed for hours after the crash. Conditions worsened with a separate multi-vehicle accident at 9:45 p.m. near the Woodhaven Road exit, which shut down traffic on southbound lanes as well, representatives from PennDOT said.
The accidents took place in the middle of a busy holiday-weekend law-enforcement campaign targeting drivers in Montgomery, Delaware and Philadelphia Counties. State police troopers were set to focus enforcement efforts on deterring drivers from speeding, encouraging seatbelt use and discouraging drunken driving.
The results of those efforts were to be made available Monday.
Contact Aubrey Whelan at 215-495-5855, at awhelan@philly.com or on Twitter at @aubreyjwhelan.