Antonio Brown, WR, Steelers vs. Chargers. With Ben Roethlisberger back in the saddle, his go-to target belongs in your lineup. We've seen Big Ben perform well when hurt, and Brown now has a solid game under his belt after returning from an ankle injury. San Diego won't put up much resistance.
Mike Williams, WR, Buccaneers vs. Eagles. These are difficult times for Eagles fans, but it's all good news for opposing fantasy players. Josh Freeman should have a field day against Philly's imploding secondary, leading to great outings from both of his favorite wideouts.
More thumbs up (excluding the no-brainers): QBs Joe Flacco, Andy Dalton, Andrew Luck, Russell Wilson, Matt Stafford, Josh Freeman; RBs Michael Turner, C.J. Spiller, Ahmad Bradshaw, Bryce Brown, Chris Johnson, Trent Richardson, Mikel Leshoure, Steven Jackson, Alfred Morris; WRs Torrey Smith, Anquan Boldin, Greg Jennings, Pierre Garcon, Hakeem Nicks, Michael Crabtree, Lance Moore.
Roll 'em back
Tony Romo, RB, Cowboys at Bengals. He's riding a two-game hot streak courtesy of a pair of pitiful pass defenses. This Sunday, Romo will be running for his life, or watching the game from his backside, as Cincinnati's league-leading sack attack overwhelms the Cowboys' sorry offensive line. He'll be lucky to emerge intact.
Beanie Wells, RB, Cardinals at Seahawks. With John Skelton back under center, Arizona's offense should move from putrid to mediocre. So you can expect more than the 22 yards Wells delivered against the Jets - but not enough to justify starting him. Seattle's run defense isn't awesome, but it's good enough to ground this rushing attack.
Reggie Bush, RB, Dolphins at 49ers. It could be an ugly afternoon for the Dolphins when they travel cross-country to face the NFL's third-best run defense. Bush has been up and down all season - mostly down - so there's little reason to believe he'll score just the fourth rushing TD of the season against this unit.
Danario Alexander, WR, Chargers at Steelers. It's hard to sit one of the hottest receivers in the business, but this is a scary matchup for his team. Philip Rivers is on a three-game slide, and he'll be facing the league's stingiest pass defense. Consider a safer option for Alexander.
Miles Austin, WR, Cowboys at Bengals. Remember what I said about Romo? By hook or crook, he'll find a way to get the ball into the hands of Dez Bryant and Jason Witten. But Austin has clearly fallen down the pecking order, making his prospects for success dim.
More thumbs down: QBs Philip Rivers, Cam Newton, Ryan Fitzpatrick, Ryan Tannehill, Sam Bradford; RBs Ryan Mathews, Mark Ingram, Rashad Jennings; WRs Brandon Lloyd, Brian Hartline, Steve Smith, Chris Givens, Malcom Floyd.
Taking a flier
Kenny Britt, WR, Titans at Colts. Most of us gave up on Britt a long time ago. But perhaps it's time to give him another look. He has scored in consecutive weeks, despite catching just five balls. Facing a weak Colts secondary, Britt has a good chance to pay handsome dividends.
Don't be the idiot who . . .
hangs onto Percy Harvin, now that he's been exiled to injured reserve. Drop him and pick up a sleeper, say T.Y. Hilton, who could potentially help your team through a postseason run. Anyone is preferable to a guy with "IR" by his name.
Follow Ladd Biro at the Fantasy Fools blog (fantasy-fools.blogspot.com), on Facebook and on Twitter @ladd_biro.