"He and his wife couldn't believe it," lottery official Karen Bach said. "They checked the numbers over and over again - absolutely shocked."
Bach said the man is financially savvy and wants to take time to make a solid financial plan, including setting up a charitable entity to aid causes that he and his wife support.
They told lottery officials they likely would keep working.
The ticket was sold at a convenience store in Fountain Hills, northeast of Phoenix.
A Missouri couple, Mark and Cindy Hill, already have claimed their half of the multistate Powerball prize.
The jackpot was the second-largest in U.S. history and set off a nationwide buying frenzy. At one point, tickets were selling at nearly 130,000 a minute.
Before the Nov. 28 drawing, the jackpot had rolled over 16 consecutive times without any winners.
In a Mega Millions drawing in March, three ticket buyers shared a $656 million jackpot, the largest lottery payout of all time.
Lottery officials said Friday that the second winner is a professional, lived in Pennsylvania until about a year ago, and only played the lotto twice since moving to Arizona.
He quickly decided to claim the money this year - as opposed to waiting until 2013 for tax reasons - because "he did have concern with the uncertainty with the fiscal cliff in 2013," Bach said.