"I worry about establishing a tradition and then losing it," said Natale. "I don't want to be negative, I want to be positive and bring what we have here to somewhere else."
Natale said he sent six players to college last season on scholarship, including linebacker Robert Kralle who earned a full-ride to Bloomsburg.
Vaux features one of the city's top backcourts in senior point guard Rysheed Jordan and shooting guard Sammy Foreman.
Jordan will be unaffected by the closure, but Foreman will be looking for a new school in September. Foreman, who transferred earlier in the school year from Haverford School, is receiving college interest from Temple, UCLA, and Rutgers.
Also slated to close is Germantown, Strawberry Mansion, University City, Douglas, Lamberton and Carroll.
Longtime Strawberry Mansion head coach Gerald Hendricks said he had no idea that his former school was going to close.
"I was proud of it," said Hendricks. "I think the school was a great place for the students and the community."
Hendricks retired in 2010 after 41 years in the District. He started at Mansion in 1980 and picked up 425 wins along the way.
In 2002, he captured his second league title behind senior guard Maureece Rice. Rice finished his career with 2,681 points which ranks as the city's all-time scoring leader.
"He was a great player and a great person," said Hendricks. "It's always good when you have talent."
Frank Greco, who coached basketball for 28 years at Central, said the closures will affect the sport's traditional rivalries.
Greco retired in 2010 after 14 years as boys' coach and 12 years as girls' coach.
"Central-University City [girls' basketball] was a great rivalry," said Greco. "When we played each other during the regular season and playoffs, it was a war. We knew we had to get through each other to move on."
Contact Matt Breen at email@example.com or @matt_breen on Twitter.
Rick O'Brien also contributed to this article.