Quarterbacks coach Clyde Christensen called the plays Sunday in Arians' absence.
"From the information that I recently received, Bruce is fine," Pagano said after the game. "They are going to keep him, I guess overnight, just for observation."
Arians, a successful offensive coordinator in the NFL for years, was praised for the way he filled in for Pagano while the first-year Colts coach was being treated for leukemia. Arians guided the team to a 9-3 record in Pagano's absence.
Arians coached Temple from 1983 to 1988. Before he joined the Colts this season, Arians spent eight years with the Pittsburgh Steelers, three as wide receivers coach and five as offensive coordinator.
Arians earned the reputation of working well with quarterbacks, something that continued this season in Indianapolis with prized rookie Andrew Luck.
The Colts enjoyed a stunning turnaround, improving from 2-14 last season to 11-5 this year.
Colts players did not want to use Arians' absence as an excuse for the loss.
"Obviously it wasn't an ideal situation, but it's not an excuse," Luck said. "Clyde did a great job.
"Coach Arians meant so much to us this year," Luck said. "It would have been great to have him here, but our attitude all year has been 'Next man up.' "
Wide receiver Reggie Wayne said that the Colts still had their opportunities, even without Arians, but he also pointed out how vital Arians has been to the Colts' success.
"This is his offense, he put it together, and he has a knack for it," Wayne said. "So I wish we would have had him, but we didn't."
Contact Marc Narducci at firstname.lastname@example.org, or follow on Twitte @sjnard.