The all-star reserves will be announced on Thursday and Holiday aided his effort with another in a series of sensational efforts.
"That is my goal that I would like to have," Holiday said about making the all-star team. "If I have to do this every game for our team to win, so be it. I will give my all every game."
In the overtime, he hit 4 of 6 shots from the field, including a three-pointer, and 3 of 4 from the foul line.
"Jrue was terrific," coach Doug Collins said.
Whether this is the type of game that can turn a spiraling season around remains to be seen, but the Sixers put forth the type of effort rarely seen in recent outings.
Entering the game with just one win in their previous seven games, the Sixers are now 17-23.
Trailing by 19 points early in the third quarter and by 92-82 with a little more than five minutes remaining in regulation, the Sixers got to within 92-90 on Young's dunk following his own steal with 2 minutes, 53 seconds left.
Toronto's Ed Davis then made a short jump hook, extending the lead to 94-90 with 2:09 remaining.
The Sixers failed to score on their next two possessions, but Young's dunk with 10.6 seconds left cut the margin to 94-92.
Toronto's Alan Anderson hit two free throws with 8.8 seconds left, extending the lead to 96-92. Spencer Hawes followed Young's miss, making it 96-94 with 5.9 seconds remaining.
Toronto's Jose Calderon threw the ensuing inbounds pass out of bounds while looking for Anderson, who was defended by Nick Young.
That gave the Sixers the ball with 5.5 seconds left. Holiday tied the score on a driving layup with 1.9 seconds left, and Kyle Lowry's half-court shot bounced off the rim at the end of regulation.
"Coming back like that for any game feels really good, down 19 and even going into overtime and winning says a lot about us and will build our confidence," Holiday said.
Holiday scored the first basket of the overtime on a steal and driving layup. Then both teams went cold until Holiday hit a pull-up jumper with 1:55 left.
Jose Calderon then hit a long three, cutting the Sixers' lead to 100-99. Holiday answered with a three of his own, and it was 103-99 with 1:28 left.
Lowry missed a three, and when Holiday drove down the lane for a basket, the Sixers led by 105-99 with 56.9 seconds left.
"I was feeling it," Holiday said.
That was evident in another performance that will surely be among the best on his all-star resumé.
Contact Marc Narducci at firstname.lastname@example.org, or follow on Twitter @sjnard.