VCU 69, La Salle 50 - The host Rams used a 23-2 run to take a decisive lead in the first half and overwhelmed the Explorers in an A-10 contest
La Salle's Shanel Harrison posted a double-double, leading all scorers with 20 points and 10 rebounds.
Virginia Commonwealth (10-15, 3-7) had four players who each scored 11 points: Adaeze Alaeze, Jessica Pellechio, Robyn Parks, and Janniina Koivunen. The Explorers fell to 8-17, 4-6.
Delaware 66, William and Mary 44 - The visiting Blue Hens ripped the Tribe to record their 33d straight regular-season win in Colonial Athletic Association play.
The No. 20 Blue Hens (22-3, 13-0) were led by Elena Delle Donne's 24 points as they won their 17th straight. The Tribe fell to 6-18, 4-9.
Notre Dame 87, Marquette 49 - The second-ranked Fighting Irish (24-1, 12-0 Big East) rolled to their 19th consecutive win with a pounding of the host Golden Eagles (12-13, 4-8).
Notre Dame was paced by Skylar Diggins, who scored 23 points to pass Katryna Gaither for second place on the school's career scoring list. Diggins has 2,131 points, trailing Irish assistant coach Beth (Morgan) Cunningham, who has 2,322.
Duke 81, Wake Forest 70 - The No. 5 Blue Devils survived losing star Chelsea Gray to a knee injury in the first half, beating the visiting Demon Deacons to remain unbeaten in the Atlantic Coast Conference.
Duke (24-1, 14-0) was led by Tricia Liston, who scored a career-high 29 points with five three-pointers. Gray was hurt with 8 minutes, 7 seconds left in the first half when she collapsed, clutching her right knee.
Chelsea Douglas scored a career-high 24 points, including five three-pointers, to lead the Demon Deacons (11-15, 4-10).
Georgia 62, Florida 57 - The No. 13 Bulldogs (21-4, 9-3 Southeastern Conference) broke a 55-55 tie with about two minutes remaining to beat the host Gators (15-11, 4-8).
Florida St. 80, North Carolina 73 - In SEC action in Tallahassee, Fla., Leonor Rodriguez scored 22 points and Chelsea Davis had 21 to lead the No. 19 Seminoles (20-5, 10-4) over the No. 14 Tar Heels (23-4, 11-3).
West Virginia 68, Iowa St. 66 - The visiting Mountaineers (15-10, 7-7 Big 12) closed with a 6-0 run to snap the No. 24 Cyclones' four-game winning streak. Iowa State (18-6, 9-5) failed to take a shot during that run, and committed six turnovers in the final 1:52 to seal the loss.
Louisville 81, DePaul 55 - The No. 10 Cardinals (21-5, 9-3 Big East) easily avenged an 86-80 loss last month to the visiting Blue Demons (18-8, 7-5). Bria Smith scored 21 points and Sara Hammond had 17 points and 13 rebounds for the hosts.