The victim, whom police did not identify, was found on the 3300 block of North Fifth Street with wounds to his chest and back.
The Manayunk shooting occurred about 1:20 a.m. Sunday on the 4300 block of Cresson Street as the victims left the Grape Room, police said.
One, age 35, was shot three times in the chest. He was taken to Roxborough Memorial Hospital and transferred to Temple University Hospital, where he was listed in critical condition, police said.
The other, 36, was shot in the left arm and hand and was in stable condition at Temple, police said.
The 16-year-old was shot in the back, abdomen, and right leg about 12:05 a.m. Sunday outside the North Garden Chinese take-out restaurant on the 5600 block of Blakemore Street. The youth, who ran into the restaurant and collapsed on the floor, was in critical condition at Einstein Medical Center, police said.
In the stabbings, a 27-year-old man was wounded in the head and lower back in a Kensington house on the 3200 block of North Lee Street near East Allegheny Avenue about 2 a.m. Sunday, police said. He was in critical condition at Temple, police said.
The other victim, a 50-year-old man, was stabbed twice in the chest about 11:25 p.m. Saturday on the 200 block of Rosemar Street in Olney, police said. He was in stable condition at Einstein Medical Center.
Police said an arrest had been made in that attack, but provided no details.
Contact Sulaiman Abdur-Rahman at email@example.com or follow on Twitter @sabdurr.