Entering Thursday's game with a 119 passer rating along with four touchdown passes and no interceptions, Vick struggled for consistency in the passing game from the start.
On the Eagles third play of their first series, Vick's intended pass to Brent Celek was tipped by Chiefs linebacker Derrick Johnson and picked off by Eric Berry, who returned the interception 38 yards for a touchdown.
Before the game was four minutes old, the Eagles found themselves in a 10-0 hole.
This was a signal of what lay ahead.
The only thing that saved both Vick and the Eagles from a total blowout was the Eagles running game. While he struggled throwing, Vick was electrifying running the ball. He finished with 95 yards rushing on just five carries.
The Eagles offense was also boosted by LeSean McCoy who rushed for 158 yards and a touchdown.
Despite the impressive work on the ground, it was the passing game that looked nothing like the explosive attack of the first two games, when the Eagles scored 63 points.
The Eagles first touchdown was set up when Vick dashed 61 yards on first down to the Chiefs' 26-yard line. After a 4-yard gain by LeSean McCoy, Vick had his best throw of the evening, finding Jason Avant in the left corner of the end zone.
Trailing, 13-6, in the second quarter, Vick threw an interception to Sean Smith, who had intended receiver Riley Cooper smothered.
Still, after three quarters, despite having committed four turnovers, the Eagles trailed by just 16-9. Vick wasn't doing much in the passing department, having thrown for 149 yards and possessing a 45.5 passer rating.
It didn't get much better in the fourth quarter.
A true sign of desperation came when the Eagles had a fourth and 20 from their own 20-yard line with 2 minutes, 41 seconds left, trailing by 26-16. Vick threw behind Avant, and the pass was almost intercepted by former Eagle Quintin Demps.
Vick wasn't helped by the fact that he faced consistent pressure. He was sacked five times on a night that nothing seemed to work well for the passing game.
Contact Marc Narducci at firstname.lastname@example.org. Follow @sjnard on Twitter.