Tavon Austin, WR, Rams at Cowboys. Sam Bradford is off to an outstanding start, and it's only going to get better as he and his prized rookie playmaker build their chemistry. Austin should give the ragged Dallas secondary fits on Sunday.
DeAndre Hopkins, WR, Texans at Ravens. Here's another rookie who emerged last week. With Andre Johnson coming back from a concussion, Hopkins is likely to be counted on even more against a Ravens secondary that was mauled by Denver in Week 1.
More thumbs up (excluding the no-brainers): QBs Tony Romo, Eli Manning, Matt Schaub, Carson Palmer, Matt Stafford, Sam Bradford, Colin Kaepernick, Robert Griffin III; RBs Darren Sproles, Chris Johnson, DeAngelo Williams, Frank Gore, Giovani Bernard; WRs Mike Wallace, Marques Colston, Hakeem Nicks, Eddie Royal, Jordy Nelson, Anquan Boldin, Stevie Johnson, Julian Edelman, and Pierre Garcon.
Roll 'em back
Russell Wilson, QB, Seahawks vs. Jaguars. Seattle can probably win this game without throwing a single pass. Marshawn Lynch will eat the Jags for lunch, giving Wilson little reason to air it out. He threw just 19 passes against the 49ers.
Darren McFadden, RB, Raiders at Broncos. He looked great against the sorry Jaguars and was solid in the opener against Indy. Now he faces the NFL's stingiest run defense, which has allowed just over 40 yards per game on average.
Stevan Ridley, RB, Patriots vs. Buccaneers. This season has been a disaster so far for Ridley and his disgruntled owners, and he narrowly avoided a total meltdown by bobbling a pitch near the end of last week's game. Tampa Bay is playing solid run defense, while Ridley is barely managing to hold onto his job.
DeMarco Murray, RB, Cowboys vs. Rams. Some will point to Murray's 253-yard coming-out party against the Rams two years ago as reason to start him. But a look at the current state of affairs may be more apropos. Murray hasn't had a 100-yard rushing game since the 2012 season opener.
Mike Williams, WR, Buccaneers at Patriots. Josh Freeman is at odds with his coach and he's not helping his cause with his mediocre play. After a solid opener, Williams disappeared in Week 2. Now he'll face a Patriots secondary that has played well against subpar passing attacks.
More thumbs down: QBs Jay Cutler, Ben Roethlisberger, Josh Freeman, Terrelle Pryor; RBs Pierre Thomas, Daryl Richardson, David Wilson, Lamar Miller, James Starks, Jacquizz Rodgers, Steelers RBs; WRs Roddy White, Greg Little, Cecil Shorts, Rod Streater, Greg Jennings, Golden Tate, Sidney Rice, and Kenny Britt.
Taking a flier
Bernard Pierce, RB, Ravens vs. Texans. Even if Ray Rice gives it a go with his painful hip flexor, Pierce will have a larger-than-normal role. Houston's run defense has been nothing special, while Pierce, a Temple product, has proved to be a solid complement to the starter.