DiLisio finished fourth last year and third as a freshman. She finished sixth at last week's District 1 qualifier.
Pennsbury's Jackie Rogowicz placed second with a two-day score of 150 and a final round of 4-over 76.
Erica Herr, the two-time defending state champion from Council Rock North, entered the final hole with a 1-stroke lead but double-bogeyed. She finished tied for third with a combined score of 151 after a final-round 76.
Owen J. Roberts' Maddie Sager tied for fifth with Radnor's Brynn Walker. The sophomores each shot a two-day score of 160. Council Rock North's Madeline Herr finished ninth.
DiLisio's great-grandfather, Nick Ciocca, was Ben Hogan's caddie at the 1950 U.S. Open when Hogan hit his famed 1-iron shot at Merion Golf Club's 18th tee. She volunteered last summer to be a standard bearer when the Open returned to Merion.
DiLisio will have a chance at another title on Wednesday when Mount St. Joseph returns to Heritage Hills for the five-team Class AAA state team championships.
In Class AA, defending champion Cara Basso of Villa Maria finished seventh with a two-day score of 170.
On Wednesday, Villa Maria and Gwynedd Mercy will compete in the five-team Class AA state team championships at Heritage Hills.
District 1 Class AAA Soccer
Monica Borzillo ripped an overtime goal from 20 yards, and Conestoga held off visiting Mount St. Joseph, 2-1, the first round of the playoffs.
It was the ninth overtime goal for the Pioneers this season and their fourth overtime win. Conestoga's Katelyn Perz scored from 20 yards to force overtime.
Unionville 1, Upper Dublin 0 - Caroline Miller took a pass with her right foot midway through the second half before drilling a shot with her left to lift the visiting Indians.
Janine Mueller assisted on the goal, which came from 14 yards. Adrianna Weber posted a nine-save shutout.
Alexis Rama had five saves for Upper Dublin.
West Chester Rustin 4, Harriton 0 - Cait Oswald dished out three assists, and the host Golden Knights scored twice in each half to win.
Maddie Moran scored once and assisted on another goal. Cassie Cheeseman, Ashlyn Kearney, and Mackenzie Moore each scored once. Charlotte Elrod and Julie Griesemer combined for five saves.
Central Bucks East 5, Interboro 0 - Forward Shaun Kane scored three times to pace the host Patriots.
Kennedy Cusato and Nicole Pannella each added a goal. Paige Marcinkoski and Katie Dolls combined for a five-save shutout.
District 1 Class AA Field Hockey
Brooke Rotelle scored twice and Eliza Wilkins recorded six saves to lead host Christopher Dock past St. Basil, 4-0, in the first round.
Jill Bolton and Karalyn Schmidt added one goal each. Stephanie Liebel had 11 saves for Basil.
Merion Mercy 6, Delco Christian 0 - Lauren Thomas, a sophomore, posted a two-save shutout, and the host Golden Bears cruised.
Merion had six goal scorers: Kelli Gogdin, Cathy Gormley, Kolbe Keating, Marisa Martinelli, Olivia Nostrant, and Emily Sigfried.
New Hope-Solebury 3, Lower Moreland 1 - Annie Behre, Kerry Leonardi, and Brianna McGarry scored goals for the visiting Lions.