Jeffrey is completely blind in at least one eye and can possibly see shadows in the other. To compensate, according to veterinarians, he leans on Jermaine and follows his brother around when they are in unfamiliar territory.
"These guys are bonded, and Jeffrey really is dependent on Jermaine at this point," said Ray Little, lifesaving director of Philadelphia's Operation Ava animal shelter. "When they are separated, they get really insecure."
Just a few weeks ago, the 35-pound strays were rescued from the streets of West Philadelphia and placed in Operation Ava's no-kill shelter on North Third Street, where they were named.
Today, they are a viral sensation on Facebook.
Even people from the United Kingdom, where pit bulls are banned, have expressed a desire to adopt Jermaine and Jeffrey, Little said.
"The amazing part of the story is the brother who is sighted," Hickey said. "He just taught himself how to be the seeing eye of his brother."
For all of the fascination and excitement over this tale of puppy love, no one as of Sunday afternoon had completed an application to adopt the brothers.
"I wish people realized that just because you've seen them doesn't mean they've been adopted," said Cary, 28, who posted the Facebook photos Thursday and Friday on the request of Operation Ava. "They still need somebody to come rescue them."
Jermaine and Jeffrey both had demodectic mange, a parasitic skin disease caused by microscopic mites, but they are "happy" and in "very good health now," Little said.
The dogs will be held indefinitely at Operation Ava until a qualified person comes forward with a willingness to adopt both for $275, Little said.
"They obviously have some sort of innate bond," said Emily Simmons, executive director of the Chester County SPCA, "and it will be wonderful to see them adopted together."
Anyone interested in adopting can contact Operation Ava at 215-240-1240.