Route 202 reopened after a multi-vehicle crash closed portions of the road in Tredyffrin, Chester County, earlier Tuesday.
The crashed created a commuter nightmare on one of the region's most-heavily traveled highways, PennDot reported.
Four hours after the pileup in the construction zone just north of the Cedar Hollow Road overpass, all Route 202 lanes were open.
One person seriously injured in the crash was flown by helicopter to Reading Hospital and is in stable condition, police said. Three others were treated for non-life threatening injuries at Paoli Memorial's trauma center, and are all expected to be released.