The program has drawn protest from two dozen local religious, political, veterans, and antiwar groups.
Robert Smith of the Brandywine Peace Community said he feared the drone program could make Horsham "a viable target" for terrorists.
"The drone strikes have involved the destruction of targets - people. The killing of people, including children," he said. "The reality of war is that the violence that is done to your enemy returns to you."
Bud Smith, a longtime Horsham resident, laughed off the concern about terrorist retribution.
"We can handle them," he said, adding that after the redevelopment, "they'll be stuck in traffic like the rest of us."
The development plan preferred by local officials and residents would add an estimated 3,355 residents and nearly 500 acres of retail, office, and entertainment space.
"It's mind-boggling, the amount of traffic it's going to bring," said Jean Caputo.
Keith Grimes of Hatboro was concerned about environmental remediation, recalling that the Navy Yard cleanup in Philadelphia "ended up being far more expensive than they ever anticipated."
"But that was 15 or 20 years ago, so maybe they've learned a thing or two since then," he added.