Louisville (24-4, 13-2) jumped out to a 24-6 lead with 12:53 left in the first half. The Owls cut it to 30-21 on Cummings' baseline jumper with 5:37 left, but another Cardinals run, this one by 8-0, made it a 17-point game with 3:15 remaining.
Temple trimmed Louisville's lead to 11 in the first minute of the second half, but the Cardinals soon eliminated any hope for a comeback. The hosts, who boast one of college basketball's toughest defenses, held Temple to 13-of-33 shooting in the second half and grew the lead to as many as 29 points.
"You have to really pay attention to details," Temple coach Fran Dunphy said. "They speed, they really speed you up."
Cummings said the Owls took some bad shots in the second half. But Louisville's defense also put them in more half-court settings, which disrupted the flow of the offense.
"That's what they tend to do on defense," Cummings said.
For the third time in four games, Temple was without the services of starting forward Anthony Lee because of an injured toe on his left foot. The conference's leading rebounder participated in pregame activities but ended up not dressing for the game. Dunphy said getting Lee back to health was his top concern.
On Saturday night, the Owls host Houston, which upset No. 21 Memphis, 77-68, on Thursday.