Wells, a junior, was a first-team National Junior College Athletic Association all-American at ASA College before enrolling at Temple.
Rhule also said that Nate L. Smith, Wells' backup, also suffered a leg injury, as did starting strong safety Boye Aromire.
"If we were to play today he wouldn't play so we'll just have to wait and see," Rhule said of Smith. "Him and Boye. I'm not sure either one of them can play to be quite honest."
Two other players who would not play if the Owls had a game today are starting wide receivers Jalen Fitzpatrick and John Christopher.
The Owls host Navy at 1 p.m. Saturday at Lincoln Financial Field in their home opener. The Midshipmen, with their dangerous triple-option offense, are coming off a 34-17 loss to No. 6 Ohio State in which they rushed for 370 yards.
The news on the offensive side of the ball wasn't very good, either. Rhule said that starting receivers Jalen Fitzpatrick and John Christopher suffered injuries that held them out of practice on Monday.
"There are quite a few guys at those skill positions who, if we had a game today, would not play," Rhule said.
Notes. Defensive back Tavon Young earned American Athletic Conference defensive player of the week honors on Monday. Young, who last season had one of Temple's three interceptions, picked off two that led to Temple scores in the win over Vanderbilt. . . . Quarterback P.J. Walker also picked up an honorable mention. Walker completed 23 of 34 passes for 207 yards and two touchdowns and rushed for 21 yards and a touchdown. . . . Defensive tackle Averee Robinson was named the College Football Performance national defensive performer of the week. Robinson recovered two fumbles, returning one for a touchdown.