November 9, 2010 |
Avid Radiopharmaceuticals Inc., a local biotech start-up rooted in a doctoral student's desire to find an early diagnosis for Alzheimer's disease, is being purchased by Eli Lilly & Co. for an initial $300 million. The deal calls for investors to receive an additional $500 million if certain commercial and regulatory milestones are reached, including Food and Drug Administration approval for Avid's groundbreaking diagnostic chemical, florbetapir F 18. Florbetapir is a radioactive compound that binds with amyloid plaque, which is present in the brains of all Alzheimer's patients.
August 24, 2011 |
BILOXI, Miss. - Glen Campbell is having a great time. Make no mistake, it is tragic that Alzheimer's disease is slowly stripping away the memories and abilities that define one of music's greats. But day to day, surrounded by family and friends, encouraged to play his guitar and sing and golf and joke, Campbell, 75, is often smiling. "I'm really not worried about anything," he said. "You know those people who say, 'Oh, geez, I wonder what's going to happen tomorrow?' Tomorrow's cool.
September 23, 2013 |
Carol Burg loves them all, but all of them would gladly go back to the lives they had before meeting her. Before Alzheimer's. "They're my angels," she says, voice pure Brooklyn, enthusiasm equally audible. "I love, love, love them. " Burg, 47, is assistant activities director in the Wellspring Memory Care building at Juniper Village, an assisted-living complex in Williamstown. The Voorhees resident has worked for three years at Wellspring, home to 36 people between the ages of 59 and 99. All have been diagnosed with end-stage dementia and are at risk of "elopement," a genteel euphemism for running away.
March 16, 1995 |
A federal appeals court yesterday ruled that a district court judge might have erred in granting a new trial to Fair Acres nursing home in a case involving an Upper Darby woman with Alzheimer's disease. The ruling could turn out to be a victory for elderly Alzheimer's patients like Margaret Wagner, a 65-year-old woman refused admission to Delaware County's Fair Acres facility because the nursing home said she had behavioral problems the home could not accommodate. Wagner's husband sued Fair Acres nursing home in 1993, alleging that the home's refusal to admit his wife of 46 years constituted discrimination by a publicly funded county facility.
December 4, 1991 |
In the 1950s and 1960s, Jack Rensel was a player on the Philadelphia scene: a key figure in the efforts to keep the baseball Athletics in Philadelphia, co-creator of a theme song for the Philadelphia Phillies, a high-profile advertising executive. He was a vibrant and bustling man. Newspapers of the time frequently alluded to his "hustle. " Then the newspaper articles about Rensel stopped. He dropped out of sight. It turned out he was a victim of Alzheimer's disease. Far from the glare of publicity, Rensel slowly dwindled, his mind and body going until he died in 1987.
December 24, 2004 |
The inability to identify the smell of lemons, lilacs and eight other common scents predicts who is most likely to get Alzheimer's disease, according to new research. People who failed to recognize these scents were at higher risk for developing Alzheimer's disease than those with more discriminating noses, the study found. Researchers measured how well people with mild cognitive impairment - memory problems that often precede Alzheimer's - could smell. Those who misidentified more than two of the 10 scents were nearly five times more likely to progress to Alzheimer's than those who did better, said Richard Doty, director of the University of Pennsylvania's Smell and Taste Center.
October 24, 1999 |
Alzheimer's disease researchers are trying to gauge the potential of a breakthrough announced Friday: the discovery of an enzyme implicated in the disease. Amgen Inc., a biotechnology company in Thousand Oaks, Calif., announced that the discovery of the beta-secretase enzyme could - perhaps in a decade - lead to drugs that block the enzyme. The company said it was too early to tell whether such drugs would be able to cure or prevent Alzheimer's disease. Almost simultaneously, SmithKline Beecham, a pharmaceutical company with U.S. headquarters in Philadelphia, was expected to announce its finding of the same enzyme at the annual Society of Neuroscience meeting, which started yesterday in Miami Beach, Fla. Scientists are not sure whether the enzyme causes Alzheimer's, so they do not know whether blocking the enzyme would cure the disease.
March 12, 2000 |
Chris Eichinger knew something was wrong when her husband backed the car out of the space on Lancaster Avenue without even glancing in the rearview mirror. Instead, he kept his eyes on her. "This isn't safe!" yelled Eichinger, then 48. "You have to watch the road!" Throughout that summer of 1996, Jack Eichinger, then 54, had had trouble finding the Acme in Wayne, a half-mile from the A-frame home where he and Chris had lived for 22 years. Chris decided it was time for Jack to see a doctor.
August 16, 1993 |
It may be difficult for some people to believe but for many years, my mother-in-law, Lillie Williams, was my best friend. Now she no longer knows me. Nor - except for brief periods - does she remember any of her relatives, her six children or her husband. She has Alzheimer's disease, a relentless degenerative brain disorder that strips its victims first of their memory, then cognition and finally physical functioning. Researchers announced last week that they have linked the most common form of Alzheimer's to a gene that helps process cholesterol, enabling them to identify some patients virtually certain to develop the disease in their later years.
November 21, 2003 |
You live your life, marry, and raise a family. Sylvia was 21, I was 20. Next month, we will have been married 56 years. We have had two miscarriages, one wonderful daughter, and three terrific grandchildren. We had settled into the kind of relationship that people look forward to after all these years of togetherness. Then, wham! At first, we joke about Syl's memory lapses. But her short-term memory gets worse. Also, there are flawed logic, poor judgment, and changes in behavior.