July 24, 2015
ISSUE | IRAN NUKE DEAL In region teeming with violence, hope Although it was not unexpected, the fierce rejection of the nuclear agreement by Israel's prime minister and almost all Republican senators and presidential candidates is disturbing ("Obama's reckless gamble," July 16). While much of the Middle East is a sea of uncontrollable violence, the deal is one example of careful negotiation and compromise. To be sure, this is no grand bargain. It was never intended to change Iranian support of terrorist groups.
July 12, 2015 |
A 43-year-old woman came to a hospital complaining of abdominal pain. She was in poor health generally, with serious kidney disease, insulin-dependent diabetes, vascular disease, and obesity. She also had stomach ulcers, but the pain that brought her to the hospital was like nothing she'd ever experienced. She had been taking antibiotics for a urinary tract infection and developed blisters, which suggested an allergic reaction. Hospital staff quickly found her to be in severe septic shock.
May 24, 2015 |
John, 52, had more infections than anyone else I had ever seen in the 30 years I've been practicing allergy and clinical immunology. At 5-foot-8 and 170 pounds, he didn't look sickly. He dressed in casual clothes and looked relaxed. He had an engaging smile and a firm handshake, and he seemed fit. He looked like he could run a 5K race easily. But after speaking with him for five minutes, I knew something was terribly wrong. At his first visit, John mentioned that he suffered from three to four episodes of sinusitis each year.
January 19, 2015 |
In his sixth year in the NBA, Kyle Lowry - the Villanova University standout who was drafted after his sophomore year, in 2006 - finally had the chance to play regularly. It was now March 2012, and he was a point guard with the Houston Rockets. He knew he could be a star. But that darn pain in his belly was such a distraction. For six months, the tormenting pain below his belly button had shifted from one side to the other. Like many professional athletes, he played through it. Somehow, he could no longer keep the nagging pain out his mind.
December 10, 2014 |
Merck & Co. dove deeper into the antibiotic drug market Monday when it agreed to buy Cubist Pharmaceuticals for $9.5 billion, including debt. The deal would pay Cubist stockholders $102 per share in cash, which Merck calculates is a 35 percent premium to Cubist's average closing price in the preceding five trading days. The agreement includes $8.4 billion for the shares and assumption of about $1.1 billion in company debt. Merck is based in Whitehouse Station, N.J., and has large facilities in Upper Gwynedd and West Point, Montgomery County.
September 8, 2014 |
Antibiotics are an odd category of pharmaceuticals, and Austria-based Nabriva Therapeutics is opening a Philadelphia-area office in hopes of finding a niche in that group. Some antibiotics are used only in humans, some only in animals, but some are used in both. Most adults have come to accept antibiotics so readily that the major problem is overuse. And overuse can mean developing resistance to medicine that used to be very effective. That has prompted efforts to control their use. The New York Times reported Wednesday that the chicken producer Perdue will stop giving antibiotics to its hatching chicks because they will eventually be eaten by humans, thereby contributing to the general problem of antibiotic resistance in humans.
April 7, 2014 |
Just so you know, this story is not for the squeamish. It's about the therapeutic power of poop, a concept that is, we admit, both repulsive and fascinating. Specifically, it's about using one person's "donation" to cure another's Clostridium difficile , a potentially fatal bacterial infection that is growing more common and virulent. The beneficial bacteria from a healthy person's gut can subdue the bad germs growing like crazy in a sick one's digestive system, even if many rounds of expensive antibiotics have failed.
March 30, 2014 |
A 64-year-old retired construction worker in stable health was admitted to a hospital for back surgery, which was suddenly canceled when he suffered a stroke. Over the next four months, the patient was repeatedly admitted to different hospitals in the region with varying symptoms, from vomiting and chills to cough and fever to diarrhea and stomach pain. Each time, physicians did multiple tests and found he had a bloodstream infection that originated from bacteria that normally live in the gut. Here's a synopsis.
March 27, 2014 |
CLEARWATER, Fla. - A white placard bearing his name still graced the top of the locker where he used to dress, but Kevin Frandsen was nowhere to be found yesterday. Nor is he expected to be found from this point forward, at least not at Bright House Field or Citizens Bank Park or anywhere else where players in Phillies jerseys congregate. The veteran infielder informed the organization yesterday that he had decided to decline an assignment to Triple A Lehigh Valley, a move that came as a mild surprise since it meant he was forgoing the $900,000 salary he was guaranteed to be paid for 2014.
January 26, 2014 |
Probiotics - live organisms naturally found in the human gut - have become a sensation in the supplement industry, with drugstores and supermarkets offering an array of capsules, pills, fermented foods, even cosmetics. These "good bacteria" and yeasts may help a variety of conditions, experts say, including digestive problems, vaginal infections, anxiety, atopic dermatitis in infants, and life-threatening side effects from taking antibiotics. But determining effective doses, figuring out which strains work for which conditions, and understanding the amounts of active ingredients in commercial supplements is far less clear.