May 14, 2016 |
British drug maker AstraZeneca, with North America headquarters in Wilmington, announced Thursdaythat the Food and Drug Administration has granted Orphan Drug Designation for its MEK inhibitor selumetinib for the treatment of patients with advanced thyroid cancer who fail to respond adequately to radioactive iodine. Orphan Drug status is given to drugs and biologics which treat, diagnose, or prevent rare diseases or disorders that affect fewer than 200,000 U.S. residents. One benefit of Orphan Drug status is a seven-year period of market exclusivity, if the drug is approved.
May 11, 2016 |
Death is essential for Pinkwash, the West Philly punk outfit. In 2009, vocalist and guitarist Joey Doubek lost his mother to cancer; years later, he's still dealing with grief in the form of music. On Friday, Pinkwash , which has received accolades from Pitchfork , NPR , and the Washington Post , will release its first full-length LP, Collective Sigh . It's the culmination of many things: Loss, self-reflection, and doubt. Doubek and drummer Ashley Arnwine first met in the Washington DIY music scene, where they collaborated in bands such as Mass Movement of the Moth and Ingrid . After a few years, Ingrid ended, and they went their separate ways.
May 9, 2016 |
John-Paul Dean wasn't supposed to compete in the April 19 meet to clinch a ChesMont League American Division track and field championship for Kennett High School unless he absolutely had to. The day before, the 18-year-old senior had struggled to get through practice following three days of chemotherapy at A.I. duPont Hospital for Children. His doctors wanted him to rest whenever possible. That was a bitter pill for John-Paul, a team captain. Kennett hadn't won the championship in a quarter century, but had gotten close for three years running.
May 2, 2016 |
As sleety rain kept falling, the activists anguished about whether to go ahead with plans to lie on the ground on a recent Saturday evening. Their "die-in" was intended to symbolize the fact that, despite all the progress in taming breast cancer, it still takes about 40,000 lives a year in the United States. Imagine wiping out the population of Wilkes-Barre or Atlantic City. Every year. For three decades. Still, the demonstrators had to be pragmatic. Most members of their new group, MET-UP, had metastatic breast cancer and had to be careful to protect their fragile health.
May 1, 2016 |
Suzette Shivers, 55, was battling breast cancer with chemotherapy. It was not illness, however, that cut her life short. She was beaten to death on April 1, and her Nicetown home was set on fire. The perpetrator remains at large and her family wants justice. Shivers was an outgoing person and willing to help people in the neighborhood, said her sister Nancy Brown, 37, of North Carolina. "She had a real good heart," Brown said. That may have led to her being victimized. "Sometimes she was a little too nice, too trusting," Brown said.
April 30, 2016 |
The Wistar Institute in University City will collaborate with a Swedish biopharmaceutical company, with the goal of developing new cancer therapies. The partnership with Cormorant Pharmaceuticals AB, of Stockholm, will pair Wistar's methods for analyzing tumor biopsies with Cormorant's experimental drug HuMax-IL8, which is in early-stage testing in patients at the National Cancer Institute. Wistar scientist Dmitry I. Gabrilovich and colleagues have developed a new biomarker based on understanding how myeloid suppressor cells play a major role in the regulation of immune responses.
April 18, 2016 |
Kerry McKean Kelly is on the board of Kelly's Heroes, a New Jersey-based nonprofit that raises money for pancreatic cancer research. It's been a year since my husband, Steve, died of pancreatic cancer at age 55. And still, there's a magnet on the side of our refrigerator with the phone number of the oncology hotline and Steve's wonderful nurse, Ellen. I'm not quite sure why I haven't removed that magnet. It might be that I just can't accept the finality that would bring.
April 17, 2016
The idea of a "marriage advantage" to health and happiness has existed for well over 150 years, and still appears to persist when it comes to cancer. For a pair of studies published Monday in the journal Cancer, researchers Scarlett Lin Gomez of the Cancer Prevention Institute of California and María Elena Martínez of the University of California-San Diego looked at records from about 800,000 American adults diagnosed in 2000 to 2009 with invasive cancer. They sliced the data by income, race, insurance status, and other factors and found that unmarried cancer patients are suffering from higher death rates than their married counterparts.
April 17, 2016
On April 9, the Philly NCAA Division I men's basketball coaches hosted the 13th annual Coaches vs. Cancer Gala at Philadelphia Park Hyatt at the Bellevue. Coaches vs. Cancer is a nationwide partnership with the American Cancer Society and the National Association of Basketball Coaches that engages coaches and their teams and communities to join the fight against cancer. The more than 550 attendees included St. Joseph's coach Phil Martelli, Temple's Fran Dunphy, Penn's Steve Donahue, La Salle's John Giannini, and, of course, Jay Wright, coach of the 2016 national champions, the Villanova Wildcats.