March 30, 2007 |
The race for prestige and profits in cervical-cancer vaccines intensified yesterday when GlaxoSmithKline P.L.C. formally asked U.S. regulators to approve its vaccine, Cervarix. The long-expected application to the Food and Drug Administration - for use in adolescent girls and possibly young women - puts Cervarix at least 16 months behind Merck & Co. Inc., maker of Gardasil. Cervarix has been tested and prepared for market partly at GlaxoSmithKline facilities in Upper Merion and Philadelphia, part of the U.S. headquarters of the London-based company.
January 18, 2007 |
A global marketing war over a potentially multibillion-dollar cancer vaccine is about to escalate, with its epicenter in the tranquil corporate campuses of Montgomery County. GlaxoSmithKline P.L.C. said yesterday that it would sponsor an unusual clinical trial of two cancer vaccines directly against each other to see which works better - Gardasil, made by Merck & Co. Inc., or its own experimental vaccine Cervarix, which is expected to hit the market this year. It is the kind of expensive, high-risk comparison that companies undertake only if forced to by regulators or only for a high-profit prescription drug - not for a vaccine.
September 10, 2009 |
Government advisers yesterday recommended federal approval of Cervarix, the GlaxoSmithKline cervical cancer vaccine, after reviewing studies showing it is significantly more effective than Gardasil, the rival vaccine made by Merck & Co. But Merck's product, which has had a three-year head start in the U.S. market, got another boost yesterday when the committee urged the U.S. Food and Drug Administration to expand its approval for prevention of...
November 23, 2015 |
For almost a decade, researchers have studied why a vaccine for adolescents that could prevent tens of thousands of cancers every year is so unpopular. Turns out it's not so much the cost, or safety worries, or the antivaccine movement. The biggest obstacle, studies show, is that doctors aren't recommending the HPV vaccine because they're uncomfortable talking to parents and tweens about a virus spread by S-E-X. But a blitzkrieg against the doctor deterrent is underway. The U.S. Centers for Disease Control and Prevention and other public-health agencies have major campaigns designed to educate doctors about why and how to recommend the HPV shots.
October 27, 2006 |
GlaxoSmithKline P.L.C. and AstraZeneca P.L.C. beat analysts' projections with strong quarterly results yesterday, although both sank on Wall Street because of unexpected hitches with new products. Nexium-maker AstraZeneca, based in London with U.S. headquarters north of Wilmington, said revenue was up 13 percent over the same period a year earlier, to $6.52 billion from $5.79 billion. Earnings rose 29 percent, to $1.59 billion, or $1.01 a share, from $1.23 billion, or 76 cents a share.
June 9, 2006 |
With a green light from regulators, Merck & Co. Inc. has begun deploying 1,500 freshly trained salespeople and unleashing a huge marketing campaign around a delicate topic: cancer and sex. The Food and Drug Administration approved Merck's cervical-cancer vaccine Gardasil yesterday, inaugurating a vaccine market potentially worth several billion dollars a year, with the Philadelphia area at its core. Gardasil will be manufactured and marketed from Merck's West Point complex. GlaxoSmithKline P.L.C.
June 21, 2013 |
ATLANTA - A vaccine against a cervical cancer virus has cut infections in teen girls by half, according to a study released Wednesday. The study confirms research done before the HPV vaccine came on the market in 2006. But this is the first evidence of how well it works now that it is in general use. "These are striking results, and I think they should be a wake-up call that we need to increase vaccination rates," said Thomas Frieden, director of the Centers for Disease Control and Prevention.
February 8, 2008 |
GlaxoSmithKline P.L.C. reported a 10 percent drop in fourth-quarter net income yesterday. A handful of its key drugs will lose patent protection this year, and executives are projecting a percentage decline in earnings per share in the mid-single digits for 2008. The combined cocktail of numbers drove down the company's shares in London nearly 8 percent. The company's U.S. shares fell 7.61 percent - dropping $3.49, to $42.39 - in New York. The performance could be summed up by a single drug: Avandia.
February 7, 2006 |
The Philadelphia-based research chief of GlaxoSmithKline P.L.C., the world's second-largest drugmaker, is leaving to work for a major foundation that has funded some of the company's vaccine research. Tadataka "Tachi" Yamada, 60, will become executive director of the global health program at the Bill & Melinda Gates Foundation, in Seattle, the company and foundation said yesterday. Succeeding Yamada on June 1 will be Moncef Slaoui, 46, GlaxoSmithKline's current head of worldwide business development and external research alliances, the company said.
October 26, 2014 |
If parents and their adolescent daughters knew that the HPV vaccine protects against cervical cancer, they'd be more likely to get the shots than uninformed people, right? Um, no, judging from a University of Pennsylvania study that tested the seemingly logical assumption. The yearlong study of 360 parents and teen girls from low-income, predominantly African American neighborhoods in Philadelphia found no link between knowledge about the vaccine and actual immunization, even though it was available free at city health clinics.