December 15, 1997 |
Less than four months ago, a group of Baltimore researchers announced a genetic mutation had been found that increased the risk of colon cancer for some Jewish people. The finding sent people seeking genetic testing. But now findings by researchers at Fox Chase Cancer Center in Philadelphia suggest that the mutated gene by itself does not increase colon-cancer risk. The researchers conclude in today's issue of Cancer Research that widespread screening for the gene "is likely to be excessive.
February 20, 2006 |
In the wake of the mixed results from the most ambitious, definitive study of postmenopausal women's health ever conducted, what's a woman to do? That's the question now that the federally funded Women's Health Initiative has wrapped up. It took 15 years, $725 million, 40 medical centers, and the steadfast participation of 161,000 American women ages 50 to 79. The WHI set out to test strategies touted as ways women could ward off cancer, heart disease, osteoporosis and Alzheimer's disease - "the major causes of death, disability and frailty in older women of all races.
May 13, 2013 |
Denise Benn spent Mother's Day last year enduring the effects of chemotherapy, trying to treat the cancer that invaded her colon and worried her five sons. One of those sons is Arrelious Benn, now an Eagles wide receiver and in better spirits than a year ago. One of the reasons is the health of Denise, whose cancer is in remission. On Saturday, one day before Mother's Day, Denise joined her five sons on Team Arrelious, created for the Susan G. Komen Global Race for the Cure, a 5K walk/run in his native Washington.
March 16, 2013 |
No one likes having a colonoscopy - a big reason why the colon cancer screening is underused. Nonetheless, growing research suggests that older folks are having unnecessary colonoscopies. The latest study of routine colonoscopies among people over 70 found that nearly a quarter were getting "potentially inappropriate" tests, based on U.S. Preventive Services Task Force guidelines. Those guidelines say that people at average risk of colon cancer should have a colonoscopy once a decade starting at age 50, and stop at age 75. The rationale is that the disease usually progresses slowly, so people near the end of their lives are unlikely to live longer with early detection and treatment.
November 6, 2012 |
Sharon Osbourne , who successfully battled colon cancer a decade ago, has revealed that she recently had a double mastectomy even though her breasts were cancer-free. The 60-year-old heavy-metal spouse and talk-show host tells Britain's Hello! that she was impelled to make that radical move last summer after learning that she has a gene that predisposes women to breast cancer. "As soon as I found out I had the breast cancer gene, I thought: 'The odds are not in my favor,' " Osbourne said.
March 7, 2013
"YOU HAVE colon cancer. " These are words no one wants to hear, words that will surely change your life forever. Tony Pace was in his 40s when he heard them. The good-natured Philadelphia native, husband and father of three is an industrial mechanic and exercise enthusiast. He is also a four-year survivor of colon cancer, who describes his journey as a "strange tale that began with a 2007 diagnosis of an infected prostate. " Just weeks after treatment for the infection, he awoke one morning and urinated only blood.
October 26, 2012 |
NEW YORK - Aspirin, one of the world's oldest and cheapest drugs, has shown remarkable promise in treating colon cancer in people with mutations in a gene that's thought to play a role in the disease. Among patients with the mutations, those who regularly took aspirin lived longer than those who didn't, a major study found. Five years after their cancers were diagnosed, 97 percent of the aspirin users were still alive versus 74 percent of those not taking the drug. Aspirin seemed to make no difference in patients who did not have the mutations.
November 5, 2012
Could colon cancer be a hormone deficiency disease? And could that deficiency also play a role in obesity? Thomas Jefferson University researcher Scott Waldman has been awarded a $1.2 million "provocative questions" grant from the National Cancer Institute to try to find answers. His search is focused on a hormone called guanylyl cyclase that binds to a cell "receptor," called GCC, in the intestines. The hormone activates GCC, which in turn tells intestinal cells to make more hormones.
February 28, 2008
AS A PHYSICIAN who specializes in digestive health, I'm concerned that too few people are getting screened for colon cancer. Screening rates remain low, even though Medicare, Medicaid and many private plans pay for tests. Colon cancer is the No. 2 cancer killer in the U.S. It's estimated that over 8,000 new cases were diagnosed in Pennsylvania in 2007, with over 2,700 deaths. Despite these numbers, this is one of the most preventable cancers, curable if detected early. Early detection and intervention can reduce deaths by up to 90 percent.
October 3, 1989 |
More than 3,000 lives could be saved each year if a new form of chemotherapy for colon cancer patients is used, researchers at the University of Pennsylvania and the National Cancer Institute said yesterday. In two studies involving 1,704 cancer patients, including about 100 from the Philadelphia area, researchers found that death rates could be reduced 10 percent to 15 percent if two drugs were given after surgery. The National Cancer Institute sent out a special announcement to 36,000 physicians and cancer researchers urging them to adopt the new treatment, if possible.