May 16, 2010
Arthur Caplan is director of the Center for Bioethics at the University of Pennsylvania Type genetic testing on an Internet search engine and then hang on. You will be in for quite a ride. There is an endless parade of companies touting genetic tests for everything, including determining whether your kid has the potential to be a star athlete, finding out whether your ancestors were kings or ne'er-do-wells, finding a date, optimizing your diet, or knowing what diet to use if your intake is not optimal.
March 4, 1997 |
With the cloning of Dolly the sheep focusing attention on genetic research, Jonathan Tolins' drama Twilight of the Golds is of special pertinence and interest, even if NorthStar Productions doesn't offer a version that does the play justice. Although the program gives "now" as the time frame for the play, the Twilight of the Golds is, at the current level of genetic research, a futuristic what-if proposition. The thought-provoking question Tolins poses is: If it were possible to predict with a high probability of accuracy that an embryo would produce a homosexual adult, would the prospective parents be justified in terminating the pregnancy based on that knowledge?
July 9, 2016 |
Men with metastatic prostate cancer have a surprisingly high rate of inherited mutations in DNA-repair genes, suggesting that all men with such advanced prostate cancer should be considered for genetic testing, a new study concludes. Genetic testing is not recommended for men with cancer confined to the prostate - or men whose cancer later spreads - because studies have found less than 5 percent have defective DNA-repair genes. But the prevalence of such defects among men who are initially diagnosed with metastatic prostate cancer has been unclear, according to the new study, published Wednesday in the New England Journal of Medicine by researchers from six leading cancer centers in the United States and Britain.
February 7, 2016 |
Independence Blue Cross' announcement that it will cover a complex type of genetic testing for some cancer patients thrusts the insurer into the debate about how to handle an increasing array of these expensive tests. The Philadelphia-based insurer - with 3 million members - became the largest to cover whole genome sequencing for select cancer patients. The analysis looks at the entire sequence of each tumor's DNA and identifies mutated genes. Physicians can request this for children with tumors, patients with rare cancers, and those with triple negative breast cancer or who have exhausted conventional therapies for metastatic cancer.
March 11, 2008 |
Two to four of every 100 people unknowingly carry a combination of genes that renders them unusually vulnerable to Alzheimer's disease as early as their 60s. If you want to find out whether you're one of them, the Philadelphia company Smart Genetics is about to offer a test you can order over the Web. For $399, customers receive a kit and send back a saliva sample. Within three weeks they learn whether they carry one or two copies of an Alzheimer's-associated genetic variant known as APOE4.
May 16, 2010 |
Type genetic testing on an Internet search engine and then hang on. You will be in for quite a ride. There is an endless parade of companies touting genetic tests for everything, including determining whether your kid has the potential to be a star athlete, finding out whether your ancestors were kings or ne'er-do-wells, finding a date, optimizing your diet, or knowing what diet to use if your intake is not optimal. Apparently, there is more self-discovery to be had by spitting your saliva into a cup and sending it off to be genetically analyzed than in a whole month of Dr. Drew.
December 11, 1995 |
Across the country, women and their physicians are inquiring about something that was hard to imagine only a year ago - a genetic test for susceptibility to breast and ovarian cancer. "I get calls every day from oncologists who say, 'My patients are asking me about this testing, and I'm not up on this,' " said Lynn Godmilow, a genetic counselor at the University of Pennsylvania Medical Center. Experts estimate that so far 1,000 people have had the test - a blood analysis that checks for mutations in the susceptibility gene, BRCA1, isolated 15 months ago. BRCA1 mutations - passed on by a mother or father - are believed to cause about 5 percent of the 182,000 breast cancers and 11 percent of the 21,000 ovarian cancers diagnosed annually.
October 5, 1994 |
If parents want to know their child's skin color in order to avoid having a "white" baby, should doctors try to help them? In Japan the answer to this question is yes. Hiroshi Shimuzu, a dermatologist at Keio University in Tokyo, along with a group of other physicians at Nagoya City University Medical School, has developed a pregnancy test for albinism. Albinos lack one of the chemicals necessary for making the substance, melanin, that gives human skin its various colors. Advances in genetics let Shimuzu and his colleagues discover a test to see whether a fetus is an albino.
January 16, 2004 |
The second and third victims of the man authorities call the Germantown rapist testified through tears yesterday at the trial of the man accused of binding their arms, taping their mouths shut, and assaulting them. "Please don't kill me, because I'll do anything you want me to do - I have two daughters to live for," one begged her attacker, according to her testimony. She said she pointed to a nearby photograph of the young girls, who were away with their father that night. She testified that as she was raped, she was thinking, " 'Why is he doing this to me?
May 21, 2007 |
THE DECISION to have an abortion is usually the result of pregnancy unwanted by women in difficult circumstances: young, single, in school, in abusive relationships, victims of rape or incest. There are many reasons women feel they are not in a position to raise a child at a certain point in their lives and come to this difficult choice. As the science of genetic testing has advanced, another model has emerged in which abortion has become an option for planned and wanted pregnancies as well.