August 23, 2012 |
RESEARCHERS have identified a mysterious new disease that has left scores of people in Asia and some in the United States with AIDS-like symptoms even though they are not infected with HIV. The patients' immune systems become damaged, leaving them unable to fend off germs, as healthy people do. What triggers this isn't known, but the disease does not seem to be contagious. This is another kind of acquired immune deficiency that is not inherited and occurs in adults, but doesn't spread the way AIDS does through a virus, said Dr. Sarah Browne, a scientist at the National Institute of Allergy and Infectious Diseases.
January 1, 2012
Robert Ader, 79, an experimental psychologist who was among the first scientists to show how mental processes influence the body's immune system, a finding that changed modern medicine, died Dec. 20 in Pittsford, N.Y. His death followed a long illness and complications of a fracture suffered in a fall, his daughter Deborah Ader said. Dr. Ader, who spent his entire career as a professor of psychiatry and psychology at the University of Rochester School of Medicine and Dentistry, conducted some of the original experiments in a field he named himself, psychoneuroimmunology.
October 4, 2011 |
STOCKHOLM - A pioneering researcher was awarded the Nobel Prize in medicine yesterday, three days after dying of pancreatic cancer without ever knowing he was about to be honored for his immune-system work that he had used to prolong his own life. The Nobel committee said it was unaware that Canadian-born cell biologist Ralph Steinman had died when it awarded the prize to him, American Bruce Beutler and French scientist Jules Hoffmann. Since the committee is supposed to consider only living scientists, the Nobel Foundation held an emergency meeting yesterday and said the decision on the 10 million kronor ($1.5 million)
October 22, 2012
In a sign of how far the science of cancer genomics has come, the University of Pennsylvania Health System will do genetic tests later this year on cancer cells of all patients with several types of cancer. Penn will test up to 48 genes in patients with melanoma, acute myelogenous leukemia, and brain and lung cancer, said Chi V. Dang, director of the Abramson Cancer Center. The results will reveal which patients could benefit from new drugs that work only for those with certain mutations.
August 11, 1990 |
Major new clinical trials have been approved for a controversial drug that proponents say may prolong indefinitely the lives of patients infected with HIV, the virus that leads to AIDS, Food and Drug Administration officials said yesterday. The trials for Ampligen, an anti-viral compound, will begin next month and involve a total of 135 patients in as many as eight cities, including Philadelphia, according to officials of HEM Research Inc., the Center City firm whose chief scientist, William A. Carter, is a co-inventor of the drug.
April 21, 2013 |
The seventh child to receive an experimental leukemia therapy at Children's Hospital of Philadelphia got good news last week: It worked. "Avrey Walker is cancer free!!!! A total remission!" her father, Aaron, exulted on their Facebook page. The 9-year-old from Redmond, Ore., was diagnosed at age 4 with acute lymphoblastic leukemia, a blood cancer that can be deadly within a few months if not treated. Like other children in the study at Children's, Avrey had undergone years of intermittent chemotherapy, only to relapse each time the toxic treatments ended.
October 10, 1989 |
Two pints of bone marrow from a California donor whose tissue is genetically similar to that of a Bucks County leukemia victim at Hahnemann University Hospital were flown here and given to the woman last night in a last-resort attempt to cure her disease. The patient, Deborah Kelly of Levittown, beat 20,000-1 odds when her doctors located an unidentified donor in San Francisco whose bone marrow is genetically similar, according to physicians. That genetic similarity is so statistically rare that it has never happened in the 13-year history of bone-marrow transplantation therapy in this area, Hahnemann doctors said.
May 8, 1987 |
Deaths from acquired immune deficiency syndrome have passed the 20,000 mark in the United States, the U.S. Centers for Disease Control reported yesterday. It said that by last Monday, the number of deaths from AIDS had reached 20,342. More than 38,000 people in the United States have been diagnosed as having the disease. So far, almost three-quarters of the victims have been homosexual or bisexual men, including some who also were intravenous drug users. One in six has been an intravenous drug user who was not homosexual.
July 10, 2002 |
Frogs with three legs - natural phenomenon or the result of pollution? Both forces may be at work, according to a study published yesterday by researchers at Pennsylvania State University. It is a debate that has raged for more than a decade, ever since schoolchildren and naturalists began finding what seemed to be increased numbers of frogs with grotesque deformities. Both environmental groups and conservative think-tanks have entered the fray - the former blaming pesticides and other human influence, the latter warning against a sky-is-falling mentality, noting that deformed frogs have been found since the 1700s.
June 2, 2014 |
Physicians have known for years that vaccines do not work as well in people who are suffering from a chronic infection such as malaria. Likewise, people with one kind of chronic infection tend to be more vulnerable to a second one. A new study led by University of Pennsylvania researchers fingers a key culprit in these breakdowns of the immune system: chronic inflammation. The research, published last month in the journal Immunity, reveals how long-term inflammation from one infection impairs the ability of infection-fighting T cells to form memories of any additional invaders - thereby hampering the immune system's ability to recognize and attack those invaders on future occasions.