October 4, 2011 |
STOCKHOLM - A pioneering researcher was awarded the Nobel Prize in medicine yesterday, three days after dying of pancreatic cancer without ever knowing he was about to be honored for his immune-system work that he had used to prolong his own life. The Nobel committee said it was unaware that Canadian-born cell biologist Ralph Steinman had died when it awarded the prize to him, American Bruce Beutler and French scientist Jules Hoffmann. Since the committee is supposed to consider only living scientists, the Nobel Foundation held an emergency meeting yesterday and said the decision on the 10 million kronor ($1.5 million)
October 22, 2012
In a sign of how far the science of cancer genomics has come, the University of Pennsylvania Health System will do genetic tests later this year on cancer cells of all patients with several types of cancer. Penn will test up to 48 genes in patients with melanoma, acute myelogenous leukemia, and brain and lung cancer, said Chi V. Dang, director of the Abramson Cancer Center. The results will reveal which patients could benefit from new drugs that work only for those with certain mutations.
August 11, 1990 |
Major new clinical trials have been approved for a controversial drug that proponents say may prolong indefinitely the lives of patients infected with HIV, the virus that leads to AIDS, Food and Drug Administration officials said yesterday. The trials for Ampligen, an anti-viral compound, will begin next month and involve a total of 135 patients in as many as eight cities, including Philadelphia, according to officials of HEM Research Inc., the Center City firm whose chief scientist, William A. Carter, is a co-inventor of the drug.
October 10, 1989 |
Two pints of bone marrow from a California donor whose tissue is genetically similar to that of a Bucks County leukemia victim at Hahnemann University Hospital were flown here and given to the woman last night in a last-resort attempt to cure her disease. The patient, Deborah Kelly of Levittown, beat 20,000-1 odds when her doctors located an unidentified donor in San Francisco whose bone marrow is genetically similar, according to physicians. That genetic similarity is so statistically rare that it has never happened in the 13-year history of bone-marrow transplantation therapy in this area, Hahnemann doctors said.
May 8, 1987 |
Deaths from acquired immune deficiency syndrome have passed the 20,000 mark in the United States, the U.S. Centers for Disease Control reported yesterday. It said that by last Monday, the number of deaths from AIDS had reached 20,342. More than 38,000 people in the United States have been diagnosed as having the disease. So far, almost three-quarters of the victims have been homosexual or bisexual men, including some who also were intravenous drug users. One in six has been an intravenous drug user who was not homosexual.
July 10, 2002 |
Frogs with three legs - natural phenomenon or the result of pollution? Both forces may be at work, according to a study published yesterday by researchers at Pennsylvania State University. It is a debate that has raged for more than a decade, ever since schoolchildren and naturalists began finding what seemed to be increased numbers of frogs with grotesque deformities. Both environmental groups and conservative think-tanks have entered the fray - the former blaming pesticides and other human influence, the latter warning against a sky-is-falling mentality, noting that deformed frogs have been found since the 1700s.
June 2, 2014 |
Physicians have known for years that vaccines do not work as well in people who are suffering from a chronic infection such as malaria. Likewise, people with one kind of chronic infection tend to be more vulnerable to a second one. A new study led by University of Pennsylvania researchers fingers a key culprit in these breakdowns of the immune system: chronic inflammation. The research, published last month in the journal Immunity, reveals how long-term inflammation from one infection impairs the ability of infection-fighting T cells to form memories of any additional invaders - thereby hampering the immune system's ability to recognize and attack those invaders on future occasions.
October 23, 1989 |
EMOTIONS AND CHOLESTEROL Men, repressing negative emotions may give you high cholesterol. That's according to a report in Psychology Today on a study that found that "truly low anxious" men, who are honest with themselves and others about experiencing anxiety, had fairly low total cholesterol levels. But those who tend to "put on a happy face but have trouble acknowledging their negative emotions" averaged a whopping 40 points higher. HEARING AID For those who suffer from nerve, or inner ear, deafness, a high-price, high-tech hearing device is about to come on the market.
December 24, 1997 |
Hatboro-Horsham's John Kenny is not only one of the best distance swimmers in the area, he is also one of the most determined, competitive and courageous. Last year, the youngster stepped out of a sickbed to swim the 500-yard freestyle at Penn during the PIAA District 1 Class AAA championships. Seeded first in the event, the weakened junior finished sixth in 4 minutes, 47 seconds and barely qualified for the state meet, which was his goal. Many swimmers perform while sick, but not with a 105-degree fever and a weight loss of between 10 and 12 pounds, as Kenny did. For a week before the district meet on March 1, he lay in bed as a result of the Epstein-Barr virus, which causes infectious mononucleosis.
September 12, 1999 |
It was supposed to have been Robert and Anne Gates Yarnall's dream house, but it became Anne's worst nightmare. The house in Upper Roxborough, with its landmark three-story atrium, made her sick, so sick that she exiled herself for a whole year to the studio she had once used for her painting while she waited to move to a more environmentally friendly house. Yarnall had fallen victim to multiple chemical sensitivity, meaning that just about everything around her made her sick - from the kerosene-based ink used in newspapers, to the mold spores on the pages of books, to the outside air laden with automobile exhausts, to the fragrance designed to mask the soapy odor of dishwashing detergent.