August 5, 2015 |
The long-term treatment of chronic illnesses is challenging on many levels. Among other issues, how can physicians manage dosing over many years, when some drugs can be habit-forming or become less effective over time? Preliminary research published Monday from scientists at the University of Pennsylvania's Perelman School of Medicine suggests that placebos, currently used mainly for control groups in clinical trials, may be worth another look for treatment. For chronic illnesses such as insomnia, they might be a key to increasing a drug's lifetime effectiveness.
December 31, 2014 |
A FORMER employee of ABM Janitorial Services claims in a lawsuit that he was discriminated against by the company because of his faith, race and disability. Vincent Danao, 49, of Logan, became a Hebrew Israelite in 2007. He said yesterday that after he did so, "I just began getting harassed and everything. " His lawsuit, filed in U.S. District Court in Philadelphia last month, contends that Danao faced hostility, got dumped with more work, was falsely criticized for his performance and was placed under increased scrutiny after he made his new religion known.
May 12, 2013 |
SAVAR, Bangladesh - A seamstress who survived 17 days before being rescued from a collapsed garment factory building was panicked, dehydrated, and suffering from insomnia as she recovered in a Bangladesh hospital Saturday, but was in generally good condition, according to her doctors. The rescue Friday of Reshma Begum, 19, brought a boost to the workers who had spent more than two weeks pulling decaying bodies from the rubble. By Saturday, they had resumed their grim task and the death toll surpassed 1,100 in the world's worst garment-industry disaster.
March 22, 2013 |
MAYBE HAVING all the toys isn't the best idea. As my buddy Chuck Darrow wrote about in these pages Wednesday, NBC 10 recently debuted a new helicopter called SKYFORCE 10 (all caps!) But on a Tuesday broadcast, reporter Christine Maddela and her crew got more than they bargained for: some doggy porn. Maddela was reporting on an alleged dogfighting ring in Germantown when the camera zoomed in on the backyard only to catch one dog mounting another. Bow chick-a wow wow . "You can see that one dog is . . . uh . . . chained up . . . , " Maddela said, trying to draw focus away from the copulating pooches.
January 12, 2013 |
Driving is dangerous enough without people falling asleep at the wheel, so on Thursday, the U.S. Food and Drug Administration urged patients and doctors to lower the bedtime doses of a common insomnia drug, which was prescribed about 40 million times in 2011. The new safety warnings are for the sleep drug zolpidem, which is sold as a generic and under the brand names Ambien, Ambien CR, Edluar, and Zolpimist. The new warnings came after clinical tests for a recently approved drug were coupled with tests involving driving simulators.
April 5, 2012 |
Penn grad Seth Berkowitz started Insomnia Cookies, a late-night cookie-delivery biz, during his junior year. Nine years later, he's fueling student munchie sessions at schools including Purdue, Syracuse, Yale and N.Y.U. But why should kids have all the fun? A few weeks ago he opened a Center City bricks-and-mortar location, where, gooey, soft, hit-the-spot cookies are pulled fresh from the oven until 3 a.m. daily. The chocolate chunk is the most popular, but don't miss the s'mores deluxe - a chocolate cookie dotted with graham cracker and melted marshmallow.
March 20, 2012 |
Why are 70 million Americans having trouble getting a good night's sleep? Let us count the ways: We are over-caffeinated (coffee, soft drinks, energy drinks, snacks) and over-medicated (prescription and over-the-counter drugs, including alcohol), wreaking havoc with slumber patterns. We are over-wired (video games, Web browsing, social media, texting) and overstressed (money, work, relationships, overloaded schedules), making us too restless to doze off when we should. We are overworked (longer hours, night shifts incompatible with our biological clocks)
July 17, 2010 |
Warner Brothers honchos surely smiled in their sleep Friday night at the estimated $3 million take from the limited midnight opening of Inception , starring the dreamy Leonardo DiCaprio . And there's more dough to roll in, since on Friday the film fully opened at 3,792 locations. Oh, Leo, we knew you had actorly superpowers, but in this Christopher Nolan -directed movie you actually can steal dreams. We don't know whether to say ick or take a Lunesta and pray for some REM sleep.
July 13, 2010 |
Friday's release of the psycho-action-drama-thriller "Inception" is shrouded in narrative mystery. Still, someone should be able to explain what it's about, right? Right? "Please don't ask any questions," pleads actress Ellen Page, who's in the movie. "Don't look at anything, don't sniff around. Just go see it. " Lucky for Warner Bros., Page doesn't work in its marketing department, which is doing a pretty good job of not giving away the plot to a movie it doesn't seem to understand - or, at least, know how to describe.
July 14, 2008 |
GlaxoSmithKline and Actelion Ltd announced today that they will collaborate on Actelion's treatment for sleep disorders. The collaboration has Glaxo paying Actelion $147 million, with a potential commitment of $3.3 billion. The Swiss drugmaker's almorexant is in Phase III development. Glaxo, has U.S. headquarters in Philadelphia and North Carolina. Actelion has an office in San Francisco and a clinical research site in Cherry Hill. Under the terms of the agreement, GSK will receive exclusive worldwide rights to co-develop and co-commercialize almorexant, Glaxo said in a news release.