August 13, 1999 |
Scientists at the University of Pennsylvania Medical School have discovered that a class of diabetes drugs already on the market can virtually cure ulcerative colitis in mice. The findings, which surprised researchers at Penn's Inflammatory Bowel Disease Center, have prompted the research team to begin a small clinical trial of one of the drugs, called rosiglitazone, in people suffering from ulcerative colitis. If it succeeds, the approach would be a breakthrough for the estimated 500,000 Americans who suffer from ulcerative colitis, which affects the colon, and for another 500,000 with Crohn's disease, which involves the entire gastrointestinal tract.
September 23, 2011
Horsham-based Janssen Biotech Inc., received approval from the Food and Drug Administration to sell Remicade for the treatment of children over age six who suffer from moderately to severely active ulcerative colitis and haven't responded to other medicine. Remicade is made at a plant in Malvern. Between 50,000 and 100,000 U.S. children have inflammatory bowel disease, of which 40 percent have ulcerative colitis. - David Sell
March 19, 1987 |
The health hazards of smoking are well-known, but a new study may have identified the first apparent hazard of kicking the habit - an increased risk of a rare but serious intestinal disease called ulcerative colitis. The study also shows that people who continue to smoke have a somewhat lower risk of the disease than do those who never smoked. However, those who conducted the study cautioned that it does not mean that smokers should keep smoking, because the advantages of quitting still far outweigh this single drawback.
September 24, 2011
In the Region Giant to shut 2 area stores Two Philadelphia-area supermarkets acquired in 2006 by Giant Food Stores in a sell-off by Clemens Markets will shut down in the next several weeks. The Abington Giant on York Road will close on Oct. 8, and Foodsource on Lancaster Avenue in Bryn Mawr is to shut on Oct. 22, Giant Food Stores announced. The Carlisle, Pa.-based chain called the formats of the soon-to-be-decommissioned stores "outmoded" and said employees would be offered positions in nearby newer and brighter stores.
August 3, 2012
NEWARK, N.J. - Jurors have awarded more than $1 million to a New Jersey state trooper who filed a whistle-blower lawsuit. The lawyer for retired Detective Sgt. 1st Class Brian Royster says that jurors in Essex County on Wednesday found that the State Police and Superintendent Col. Rick Fuentes violated the act, which aims to protect those who speak out. Royster, who is black, filed suit in 2005. The 48-year-old claimed that cases pending with the Equal Employment Opportunity and Affirmative Action unit were stalled without reason and troopers accused of misconduct had been allowed to retire instead of being disciplined.
June 9, 2013 |
Big pharmaceutical companies strike licensing deals with small companies in hopes of finding new, highly profitable medicine without the cost of buying a whole company. Small companies get funding other ways, such as venture capital firms, but the money from licensing arrangements can mean the difference between continuing operations and closing shop. Sometimes these deals work, sometimes not. Last week presented four examples, three starting and one ending (badly), involving the drugmakers GlaxoSmithKline, Johnson & Johnson, Pfizer, and AstraZeneca, all of which have significant Philadelphia-area operations.
October 8, 1994 |
If there's one thing Villanova seems to have gotten used to, it's knowing that it won't have the same starting quarterback an entire season. Redshirt junior Tom Marchese will make his second start today in Storrs, Conn., where Andy Talley's Wildcats (3-2 overall) will be looking to even their Yankee Conference record at 2-2 when they face Skip Holtz's Connecticut Huskies (1-4, 1-1). Villanova has not had the same starting quarterback for an entire season since Tom Colombo went 12 games in 1991.
November 25, 1995
PROPERTY OWNERS SHOULD PAY TO FIX WATER RUNOFF Stephen Kunz's Nov. 18 letter ("Save our natural resources from special interests"), about lax enforcement of environmental regulations and the sacrifice of natural resources by special interests, was on target. The latest example of such laxity and environmental sacrifice is Cherry Hill Township's proposed Kingston Estates flood-control project. The project will waste $3.4 million in public tax dollars to solve what is largely a private-property problem.
December 7, 2010
Henry G. "Buddy" Herling, 83, of Somerton, former commissioner of the Department of Licenses and Inspections, died of heart failure Thursday, Dec. 2, at Lafayette-Redeemer Hospice. Mr. Herling spent much of his career serving the city, first as an electrician, then as a firefighter for four years, before becoming a civil engineer and fire-code specialist. In 1980, he was appointed deputy commissioner of L&I, and became commissioner in 1985. After leaving the department in 1988, he was a consultant for 20 years for the Philadelphia Industrial Development Corp.
May 30, 2016 |
Editor's note: Mike Natter, a medical student at Sidney Kimmel Medical College at Thomas Jefferson University, frequently takes notes in the form of cartoons to make what he's learning more memorable. Here's how he captured, in pictures and words, a scenario he composed from his textbooks and patients he's seen during family medicine clinical rotation. Alarmed at seeing blood in the toilet after a bowel movement, a man in his late 50's went to see his family doctor. He was in no pain, and had neither nausea nor vomiting, but he was chronically constipated.